Ricerc@Sapienza

Our laboratory explores how extracellular vesicles (EVs) mediate neuroimmune communication between glial cells and neurons. We investigate their roles in brain aging and brain tumor microenvironments, combining advanced analyses of EV concentration, size, and molecular cargo with studies of uptake and release in vitro. We also track EV biodistribution in murine models to understand their systemic impact. Through this integrated approach, we aim to uncover mechanisms of neuro-glial interaction and identify novel biomarkers and therapeutic targets.