Neural stem cells in neuropsychiatric disorders
01 Pubblicazione su rivista
Sacco Roberto, Cacci Emanuele, Novarino Gaia
ISSN: 0959-4388
The precise control of neural stem cell (NSC) proliferation and differentiation is crucial for the development and function of the human brain. Here, we review the emerging links between the alteration of embryonic and adult neurogenesis and the etiology of neuropsychiatric disorders (NPDs) such as autism spectrum disorders (ASDs) and schizophrenia (SCZ), as well as the advances in stem cell-based modeling and the novel therapeutic targets derived from these studies