Forensic data and microvariant sequence characterization of 27 Y-STR loci analyzed in four Eastern African countries
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Iacovacci Giuseppe, D'Atanasio Eugenia, Marini Ornella, Coppa Alfredo, Sellitto Daniele, Trombetta Beniamino, Berti Andrea, Cruciani Fulvio
ISSN: 1872-4973
By using the recently introduced 6-dye Yfiler® Plus multiplex, we analyzed 462 males belonging to 20 ethnic groups from four eastern African countries (Eritrea, Ethiopia, Djibouti and Kenya). Through a Y-STR sequence analysis, combined with 62 SNP-based haplogroup information, we were able to classify observed microvariant alleles at four Y-STR loci as either monophyletic (DYF387S1 and DYS458) or recurrent (DYS449 and DYS627). We found evidence of non-allelic gene conversion among paralogous STRs of the two-copy locus DYF387S1. Twenty-two diallelic and triallelic patterns observed at 13 different loci were found to be significantly over-represented (p