Liquid biopsy in clear cell renal cell carcinoma. Urinary miR-210-3p as emerging specific biomarker
04 Pubblicazione in atti di convegno
Costantini M., Petrozza V., Tito C., Giammusso L. M., Sorrentino V., Cacciotti J., Porta N., Iaiza A., Pastore A. L., Di Carlo A., Simone G., Gallucci M., Carbone A., Fazi F.
ISSN: 2666-1691
Themost common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC) that accounts for 70–80% of all renal malignancies. To date, no useful markers are available in clinical practice for early diagnosis and for optimal patient stratification. MicroRNAs, a class of small non-coding RNA, are emerging as promising molecules in the management of urological tumors suggesting the possibility of using them as non-invasive biomarkers. The aim of this study is to evaluate whether miR-210-3p may be an accurate non invasive diagnostic and prognostic biomarker for ccRCC patients.