Ricerc@Sapienza

Objective: The objective of this study is to recognize representative
cranio‑cervico‑mandibular features of patients with Ehler–Danlos syndrome
and associated temporomandibular disorders (TMDs), to assess a targeted and
integrated treatment plan.
Materials and Methods: After a diagnosis of disease, 38 individiuals with
Ehler–Danlos syndrome and temporomandibular symptomatology referred were
evaluated. Gnathological evaluation, according to the Diagnostic Criteria for
TMDs, and radiographic imaging was performed. In addition, digital evaluation
of occlusal and muscular balance, using surface electromyography of jaw muscles,
was conducted. Statistical software for data analysis ‑ STATA (StataCorp, College
station, Texas, USA) ‑ was used.
Results: Most common temporomandibular dysfunctions were arthralgia, myalgia,
disc displacement with reduction and subluxation. Headache and neck pain
were the most frequent comorbidities. Somatization, depression, anxiety, and
obsessive‑compulsive behavior were the most recurrent psychological disorders.
Electromyographic analysis showed out of normal range data.
Conclusion: Early diagnosis and interception are requested to avoid injuries and
repeated traumatism. Multidisciplinary treatments are available to approach all the
aspects of the syndrome.