Case-report. Metastases in a low-stage middle-graded HCC in cleared HCV infection, non-cirrhotic liver. Surgical therapy

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Brozzetti Stefania, Bini Simone, Fazzi Katia, Chiarella Leonardo Luca, Ceccarossi Virginia, De Lucia Chiara, De Toma Giorgio
ISSN: 2210-2612

Introduction
Hepatocellular carcinoma (HCC) is rare in non-cirrhotic liver. Achievement of sustained virological response
(SVR) reduces even more the risk.
Presentation of case
Liver resection for small HCC was performed in cleared HCV infection non-cirrhotic 62-year-old man.
Methacronous oligometastatic recurrences in intolerant to Nexavar® side-effects patient, were treated by multiple
innovative microinvasive approaches: bilateral laparoscopic adrenalectomy, thoracic wall resection, laparoscopic
sacrum cryoablation combined with hadron-therapy.
Discussion
Therapies allowed the patient to lead 6 years satisfying QoL with only a small residual presacral disease
stable at 8 months.
Conclusion
Microinvasive surgery may be a valid resource of therapy in indolent HCC limited distant recurrences.

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