Coexistence of three EGFR mutations in an NSCLC patient: A brief report
01 Pubblicazione su rivista
Belardinilli Francesca, Gradilone Angela, Gelibter Alain, Zani Massimo, Occhipinti Mario, Ferraro Sergio, Nicolazzo Chiara, Coppa Anna, Giannini Giuseppe
ISSN: 1724-6008
The epidermal growth factor receptor (EGFR) represents a molecular target for tyrosine kinase inhibitors for non-small cell lung cancer (NSCLC) patients with a mutation in the EGFR gene. Mutations of the EGFR gene that occur at a single position in NSCLC tissue are found as single, whereas two or more mutations on the same allele are poorly detected and investigated.