Interplay among IncA and bla KPC -carrying plasmids in citrobacter freundii
01 Pubblicazione su rivista
Bitar I, And Caltagirone, M. and Villa, L. and Marchetti, V. M. and Nucleo, E. and Sarti, M. and Migliavacca, Carattoli A.
DOI: 10.1128/AAC.02609-18
ISSN: 0066-4804
We report two KPC-producing Citrobacter freundii isolates from unrelated patients. In one case, bla KPC-2 was harbored on a novel variant of a Tn4401 transposon of an IncN plasmid conjugated together with a coresident IncA plasmid, whereas in the other one, bla KPC-3 was on a Tn4401a transposon located on an IncX3-IncA self-conjugative plasmid fusion. The interplay among plasmids carrying bla KPC and the coresident IncA plasmids offers new information on plasmids coresident within clinically relevant enterobacteria. Copyright © 2019 American Society for Microbiology. All Rights Reserved.