Diabetic Gastroparesis Modeling and Observer Design

04 Pubblicazione in atti di convegno
Califano C., Scharbarg E., Magdelaine N., Moog C. H.
ISSN: 2405-8963

Type 1 diabetes results from the lack of endogenous production of insulin by the pancreas.
According to various references, 4% to 12% of diabetic patients are affected by gastroparesis which
delays the digestion process. Gastroparesis is characterized by a constellation of gastrointestinal
symptoms in association with delayed gastric emptying (GE). For the first time, a mathematical model
is introduced to describe the glycemia dynamics for this significant class of patients. It is shown to yield
to a nonlinear time delay model designed for estimation and control.

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