Infections in liver and lung transplant recipients. A national prospective cohort

01 Pubblicazione su rivista
Gagliotti Carlo, Morsillo Filomena, Luisa Moro Maria, Masiero Lucia, Procaccio Francesco, Vespasiano Francesca, Pantosti Annalisa, Monaco Monica, Errico Giulia, Ricci Andrea, Grossi Paolo, Nanni Costa Alessandro, Adorno Domenico, Ambretti Simone, Amoroso Antonio, Arghittu Milena, Berloco Pasquale Bartolomeo, Bertani Manuela Bonizzoli Alessandro, Cambieri Patrizia, Canzonieri Marco, Caprio Mario, Carrara Elena, Carrinola Rosaria, Cibelli Eva, Cillo Umberto, Colledan Michele, Colombo MARIA ROSARIA, Coluccio Elena, Giulio Conaldi Pier, Cusi Mariagrazia, Maria D’Armini Andrea, Da Riva Adelaide, D'Auria Bianca, De Carlis Luciano, De Cillia Carlo, De Gasperi Andrea, Di Caro Antonino, Di Ciaccio Paola, Dondossola Daniele, Farina Claudio, Feltrin Giuseppe, Carola Finarelli Alba, Fossati Lucina, Gaibani Paolo, Garcia Fernandez Aurora, Gesu Giovanni, Giacometti Raffaella, Gona Floriana, Gridelli Bruno, Henrici De Angelis Lucia, Paola Landini Maria, Maldarelli Federica, Mancini Carlo, Marone Piero, Mularoni Alessandra, Paglialunga Giulia, Paladini Piero, Palù Giorgio, Parisi Saverio, Peris Adriano, Daniele Pinna Antonio, Platto Marco, Pugliese Francesco, Puoti Francesca, Rago Claudio, Ravini Mario, Rea Federico, Rinaldi Mauro, Rossi Giorgio, Rossi Lucia, Rossi Massimo, Salizzoni Mauro, Sangiorgi Gabriela, Santambrogio Luigi, Spada Marco, Sparacino Vito, Stella Franco, Torelli Rosanna, Torresani Erminio, Tosi Davide, Vailati Francesca, Valeri Maurizio, Venuta Federico, Vesconi Sergio, Viale Pierluigi, Vismara. Chiara
ISSN: 0934-9723

Infections are a major complication of solid organ transplants (SOTs). This study aimed to describe recipients' characteristics, and the frequency and etiology of infections and transplant outcome in liver and lung SOTs, and to investigate exposures associated to infection and death in liver transplant recipients. The study population included recipients of SOTs performed in Italy during a 1-year period in ten Italian lung transplant units and eight liver transplant units. Data on comorbidities, infections, retransplantation, and death were prospectively collected using a web-based system, with a 6-month follow-up. The cumulative incidence of infection was 31.7% and 47.8% in liver and lung transplants, respectively, with most infections occurring within the first month after transplantation. Gram-negatives, which were primarily multidrug-resistant, were the most frequent cause of infection. Death rates were 0.42 per 1000 recipient-days in liver transplants and 1.41 per 1000 recipient-days in lung transplants. Infection after SOT in adult liver recipients is associated to an increased risk of death (OR = 13.25; p-value 

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma