Antihypertensive drugs and the risk of cancer. a critical review of available evidence and perspective
01 Pubblicazione su rivista
Battistoni Allegra, Tocci Giuliano, Coluccia Roberta, Burnier Michel, Ruilope Luis M., Volpe Massimo
ISSN: 0263-6352
The issue of a potential danger of antihypertensive drugs
related to cancer susceptibility is currently generating a
major debate in the scientific community, concerns in the
public and emphasized interest from the media. The
present article is a thorough review of what is known on
the various classes of antihypertensive drugs concerning
the risk of developing different neoplasms and about the
suggested pathophysiological mechanisms, whenever
available. The main limitations of evidence derived from
studies currently available in this setting are also discussed,
high-lightening the need for newly developed approaches
to generate more accurate recommendations and informed
advice for physicians.