P2Y12 inhibitors monotherapy after short course of dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: a meta-analysis of randomized clinical trials including 29 089 patients
01 Pubblicazione su rivista
Bianco Matteo, Careggio Alessandro, Destefanis Paola, Luciano Alessia, Perrelli Maria Giulia, Quadri Giorgio, Rossini Roberta, Campo Gianluca, Vizzari Giampiero, D'Ascenzo Fabrizio, Anselmino Matteo, Biondi-Zoccai Giuseppe, Ibáñez Borja, Montagna Laura, Varbella Ferdinando, Cerrato Enrico
ISSN: 2055-6837
Dual antiplatelet therapy (DAPT) reduces the incidence of thrombotic complications at the cost of an increase in bleedings. New antiplatelet therapies focused on minimizing bleeding and maximizing antithrombotic effects are emerging. The aim of this study is to collect the current evidence coming from randomized controlled trials (RCTs) on early aspirin interruption after percutaneous coronary intervention (PCI) and current drug-eluting stent (DES) implantation and to perform a meta-analysis in order to evaluate the safety and efficacy of this strategy.