Ongoing Electroencephalographic Rhythms Related to Exploratory Movements in Transgenic TASTPM Mice
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Del Percio Claudio, Drinkenburg Wilhelmus, Lopez Susanna, Pascarelli Maria Teresa, Lizio Roberta, Noce Giuseppe, Ferri Raffaele, Bastlund Jesper Frank, Laursen Bettina, Christensen Ditte Zerlang, Pedersen Jan T, Forloni Gianluigi, Frasca Angelisa, Noè Francesco M, Fabene Paolo Francesco, Bertini Giuseppe, Colavito Valeria, Bentivoglio Marina, Kelley Jonathan, Dix Sophie, Infarinato Francesco, Soricelli Andrea, Stocchi Fabrizio, Richardson Jill C, Babiloni Claudio
DOI: 10.3233/JAD-190351
ISSN: 1875-8908
The European PharmaCog study (http://www.pharmacog.org) has reported a reduction in delta (1-6 Hz) electroencephalographic (EEG) power (density) during cage exploration (active condition) compared with quiet wakefulness (passive condition) in PDAPP mice (hAPP Indiana V717F mutation) modeling Alzheimer's disease (AD) amyloidosis and cognitive deficits.