A Coplanar Waveguide System for Drug Delivery Mediated by Nanoelectroporation: an Experimental and Numerical Study

04 Pubblicazione in atti di convegno
Caramazza Laura, Paffi Alessandra, Liberti Micaela, Apollonio Francesca

Nanosecond pulsed electric fields (nsPEFs) can interact with lipid vesicles, that are primary drug delivery nanocarriers activated by external signals. In this work, authors propose a new setup of an experimental bench suitable for nsPEFs exposure of liposome nanosystems, compliant with the wideband requirements for nanosecond pulses. A multiphysics modelling able to predict liposome poration is proposed to define the characteristics of signals to be used in experiments.

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma