Risultati ricerca pubblicazioni

1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

D'Ascenzio M., Secci D., Carradori S., Zara S., Guglielmi P., Cirilli R., Pierini M., Poli G., Tuccinardi T., Angeli A., Supuran C. T.

Phenyl(thio)phosphon(amid)ate benzenesulfonamides as potent and selective inhibitors of human carbonic anhydrases II and VII counteract allodynia in a mouse model of oxaliplatin-induced neuropathy

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Nocentini A., Alterio V., Bua S., Micheli L., Esposito D., Buonanno M., Bartolucci G., Osman S. M., ALOthman Z. A., Cirilli R., Pierini M., Monti S. M., Di Cesare Mannelli L., Gratteri P., Ghelardini C., De Simone G., Supuran C. T.

Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Bavo Francesco, Pallavicini Marco, Gotti Cecilia, Appiani Rebecca, Moretti Milena, Colombo Sara Francesca, Pucci Susanna, Viani Paola, Budriesi Roberta, Renzi Massimiliano, Fucile Sergio, Bolchi Cristiano

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Viayna Elisabet, Coquelle Nicolas, Cieslikiewicz-Bouet Monika, Cisternas Pedro, Oliva Carolina A., Sánchez-López Elena, Ettcheto Miren, Bartolini Manuela, De Simone Angela, Ricchini Mattia, Rendina Marisa, Pons Mégane, Firuzi Omidreza, Pérez Belén, Saso Luciano, Andrisano Vincenza, Nachon Florian, Brazzolotto Xavier, García Maria Luisa, Camins Antoni, Silman Israel, Jean Ludovic, Inestrosa Nibaldo C., Colletier Jacques-Philippe, Renard Pierre-Yves, Muñoz-Torrero Diego

Insights into pparγphosphorylation and its inhibition mechanism

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Montanari R., Capelli D., Yamamoto K., Awaishima H., Nishikata K., Barendregt A., Heck A. J. R., Loiodice F., Altieri F., Paiardini A., Grottesi A., Pirone L., Pedone E., Peiretti F., Brunel J. M., Itoh T., Pochetti G.