Risultati ricerca pubblicazioni

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Berardozzi Simone, Bernardi Flavia, Infante Paola, Ingallina Cinzia, Toscano Sara, De Paolis Elisa, Alfonsi Romina, Caimano Miriam, Botta Bruno, Mori Mattia, Di Marcotullio Lucia, Ghirga Francesca

Ricerc@Sapienza

Risultati ricerca pubblicazioni

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold

Design, palladium-catalyzed synthesis, and biological investigation of 2-substituted 3-aroylquinolin-4(1H)-ones as inhibitors of the Hedgehog signaling pathway.