Risultati ricerca pubblicazioni

Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells

pubblicato su: ACS MEDICINAL CHEMISTRY LETTERS - 2020

Romanelli Annalisa, Stazi Giulia, Fioravanti Rossella, Zwergel Clemens, Di Bello Elisabetta, Pomella Silvia, Perrone Clara, Battistelli Cecilia, Strippoli Raffaele, Tripodi Marco, del Bufalo Donatella, Rota Rossella, Trisciuoglio Daniela, Mai Antonello, Valente Sergio

Hedgehog signaling pathway inhibitors: an updated patent review (2015–present)

pubblicato su: EXPERT OPINION ON THERAPEUTIC PATENTS - 2020

Quaglio D., Infante P., Di Marcotullio L., Botta B., Mori M.

Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog

pubblicato su: CURRENT PHARMACEUTICAL DESIGN - 2018

Palermo Rocco, Ghirga Francesca, Piccioni Maria Grazia, Bernardi Flavia, Zhdanovskaya Nadezda, Infante Paola, Mori Mattia

Mycobacterial tryptophan biosynthesis: a promising target for tuberculosis drug development?

pubblicato su: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS - 2019

Consalvi Sara, Scarpecci Cristina, Biava Mariangela, Poce Giovanna

Novel pyrazole-containing compounds active against mycobacterium tuberculosis

pubblicato su: ACS MEDICINAL CHEMISTRY LETTERS - 2019

Poce Giovanna, Consalvi Sara, Venditti Giulia, Alfonso Salvatore, Desideri Nicoletta, Fernandez-Menendez Raquel, Bates Robert H., Ballell Lluis, Barros Aguirre David, Rullas Joaquin, De Logu Alessandro, Gardner Michelle, Ioerger Thomas R., Rubin Eric J., Biava Mariangela

In vivo potent BM635 analogue with improved drug-like properties

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Poce Giovanna, Cocozza Martina, Alfonso Salvatore, Consalvi Sara, Venditti Giulia, Fernandez-Menendez Raquel, Bates Robert H., Barros Aguirre David, Ballell Lluis, De Logu Alessandro, Vistoli Giulio, Biava Mariangela

In Memory of Maurizio Botta: his Contribution to the Development of Computer-Aided Drug Design

pubblicato su: JOURNAL OF CHEMICAL INFORMATION AND MODELING - 2019

Mori M., Manetti F., Botta B., Tafi A.

Naturally occurring diels-alder-type adducts from morus nigra as potent inhibitors of mycobacterium tuberculosis protein tyrosine phosphatase B

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Mascarello Alessandra, Orbem Menegatti Angela Camila, Calcaterra Andrea, Martins Priscila Graziela Alves, Chiaradia-Delatorre Louise Domeneghini, D'Acquarica Ilaria, Ferrari Franco, Pau Valentina, Sanna Adriana, De Logu Alessandro, Botta Maurizio, Botta Bruno, Terenzi Hernã¡n, Mori Mattia

The market of chiral drugs: chiral switches versus de novo enantiomerically pure compounds

pubblicato su: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS - 2018

Calcaterra Andrea, D'Acquarica Ilaria

Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation

pubblicato su: CHEMMEDCHEM - 2020

Fioravanti R., Romanelli A., Mautone N., Di Bello E., Rovere A., Corinti D., Zwergel C., Valente S., Rotili D., Botrugno O. A., Dessanti P., Vultaggio S., Vianello P., Cappa A., Binda C., Mattevi A., Minucci S., Mercurio C., Varasi M., Mai A.

Properly substituted cyclic Bis-(2-bromobenzylidene) compounds behaved as dual p300/CARM1 Inhibitors and Induced apoptosis in cancer cells

pubblicato su: MOLECULES - 2020

Fioravanti Rossella, Tomassi Stefano, Di Bello Elisabetta, Romanelli Annalisa, Plateroti Andrea Maria, Benedetti Rosaria, Conte Mariarosaria, Novellino Ettore, Altucci Lucia, Valente Sergio, Mai Antonello

Breakthroughs in medicinal chemistry: new targets and mechanisms, new drugs, new hopes-4

pubblicato su: MOLECULES - 2019

Mangoni A. A., Guillou C., Eynde J. J. V., Hulme C., Jampilek J., Li W., Prokai-Tatrai K., Rautio J., Collina S., Tuccinardi T., Sousa M. E., Sabatier J. -M., Galdiero S., Karaman R., Kokotos G., Torri G., Javier Luque F., Helena Vasconcelos M., Hadjipavlou-Litina D., Siciliano C., Gutschow M., Ragno R., Gomes P. A. C., Agrofoglio L. A., Munoz-Torrero D.

MAO inhibitors and their wider applications: a patent review

pubblicato su: EXPERT OPINION ON THERAPEUTIC PATENTS - 2018

Carradori Simone, Secci Daniela, Petzer Jacques P.

New perspectives from South-Y-East, not all about death. A report of the 12thlnternational Meeting on Yeast Apoptosis in Bari, Italy, May 14th-18th, 2017

pubblicato su: MICROBIAL CELL - 2018

Guaragnella Nicoletta, Stirpe Mariarita, Burhans William, Côrte-Real Manuela, Gourlay Campbell, Ludovico Paula, Madeo Frank, Petranovic Dina, Winderickx Joris, Mazzoni Cristina, Giannattasio Sergio

Natural modulators of nonalcoholic fatty liver disease: mode of action analysis and in silico ADME-Tox prediction

pubblicato su: TOXICOLOGY AND APPLIED PHARMACOLOGY - 2017

Al Sharif Merilin, Alov Petko, Vitcheva Vessela, Diukendjieva Antonia, Mori Mattia, Botta Bruno, Tsakovska Ivanka, Pajeva Ilza

Genetic up-regulation or pharmacological activation of the Na+/Ca2+ exchanger 1 (NCX1) enhances hippocampal-dependent contextual and spatial learning and memory

pubblicato su: MOLECULAR NEUROBIOLOGY - 2020

Natale Silvia, Anzilotti Serenella, Petrozziello Tiziana, Ciccone Roselia, Serani Angelo, Calabrese Lucrezia, Severino Beatrice, Frecentese Francesco, Secondo Agnese, Pannaccione Anna, Fiorino Ferdinando, Cuomo Ornella, Vinciguerra Antonio, D'Esposito Lucia, Sadile Adolfo Gustavo, Cabib Simona, Di Renzo Gianfranco, Annunziato Lucio, Molinaro Pasquale

Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs)

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2020

Tomaselli D., Mautone N., Mai A., Rotili D.