Risultati ricerca pubblicazioni

β-blockers reverse agonist-induced β2-AR downregulation regardless of their signaling profile

pubblicato su: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2020

Maccari S., Vezzi V., Barbagallo F., Stati T., Ascione B., Gro M. C., Catalano L., Marano G., Matarrese P., Ambrosio C., Molinari P.

Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts

pubblicato su: JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE - 2019

West T. M., Wang Q., Deng B., Zhang Y., Barbagallo F., Reddy G. R., Chen D., Phan K. S., Xu B., Isidori A., Xiang Y. K.

SMO inhibition modulates cellular plasticity and invasiveness in colorectal cancer

pubblicato su: FRONTIERS IN PHARMACOLOGY - 2018

Magistri Paolo, Battistelli Cecilia, Strippoli Raffaele, Petrucciani Niccolò, Pellinen Teijo, Rossi Lucia, Mangogna Livia, Aurello Paolo, D'Angelo Francesco, Tripodi Marco, Ramacciato Giovanni, Nigri Giuseppe

Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog

pubblicato su: CURRENT PHARMACEUTICAL DESIGN - 2018

Palermo Rocco, Ghirga Francesca, Piccioni Maria Grazia, Bernardi Flavia, Zhdanovskaya Nadezda, Infante Paola, Mori Mattia

A new diterpene and other compounds from the unripe female cones of Wollemia nobilis

pubblicato su: NATURAL PRODUCT RESEARCH - 2020

Venditti Alessandro, Frezza Claudio, Rossi Giacomo, Sciubba Fabio, Ornano Luigi, De Vita Daniela, Toniolo Chiara, Tomassini Lamberto, Foddai Sebastiano, Nicoletti Marcello, Di Cocco Maria Enrica, Bianco Armandodoriano, Serafini Mauro

Ethnobotany and phytochemistry of the Genus Eremostachys Bunge

pubblicato su: CURRENT ORGANIC CHEMISTRY - 2019

Mohammadhosseini Majid, Frezza Claudio, Venditti Alessandro, Akbarzadeh Abolfazl

In vivo potent BM635 analogue with improved drug-like properties

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Poce Giovanna, Cocozza Martina, Alfonso Salvatore, Consalvi Sara, Venditti Giulia, Fernandez-Menendez Raquel, Bates Robert H., Barros Aguirre David, Ballell Lluis, De Logu Alessandro, Vistoli Giulio, Biava Mariangela

Naturally occurring diels-alder-type adducts from morus nigra as potent inhibitors of mycobacterium tuberculosis protein tyrosine phosphatase B

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Mascarello Alessandra, Orbem Menegatti Angela Camila, Calcaterra Andrea, Martins Priscila Graziela Alves, Chiaradia-Delatorre Louise Domeneghini, D'Acquarica Ilaria, Ferrari Franco, Pau Valentina, Sanna Adriana, De Logu Alessandro, Botta Maurizio, Botta Bruno, Terenzi Hernã¡n, Mori Mattia

Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts

pubblicato su: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - 2018

Krasilnikova Jelena, Lauberte Liga, Stoyanova Elena, Abadjieva Desislava, Chervenkov Mihail, Mori Mattia, De Paolis Elisa, Mladenova Vanya, Telysheva Galina, Botta Bruno, Kistanova Elena

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Talapatra Sandeep K., Tham Chuin Lean, Guglielmi Paolo, Cirilli Roberto, Chandrasekaran Balakumar, Karpoormath Rajshekhar, Carradori Simone, Kozielski Frank

Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications

pubblicato su: FUTURE MEDICINAL CHEMISTRY - 2018

Fiorentino Francesco, Mai Antonello, Rotili Dante

Trends of LSD1 inhibitors in viral infections

pubblicato su: FUTURE MEDICINAL CHEMISTRY - 2018

Zwergel Clemens, Stazi Giulia, Mai Antonello, Valente Sergio

Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers

pubblicato su: PSYCHOPHARMACOLOGY - 2018

Muñoz-Cobo I., Erburu M. M., Zwergel C., Cirilli R., Mai A., Valente S., Puerta E., Tordera Rosa M.

MAO inhibitors and their wider applications: a patent review

pubblicato su: EXPERT OPINION ON THERAPEUTIC PATENTS - 2018

Carradori Simone, Secci Daniela, Petzer Jacques P.

CD28 between tolerance and autoimmunity: The side effects of animal models [version 1; referees: 2 approved]

pubblicato su: F1000RESEARCH - 2018

Porciello Nicla, Kunkl Martina, Tuosto Loretta

Qualitative and semi-quantitative phytochemical analysis on the seeds of a new Nigella sativa L. population exemplar from Iran

pubblicato su: PLANT BIOSYSTEMS - 2020

Frezza Claudio, Sciubba Fabio, Vincenti Flaminia, Montesano Camilla, Venditti Alessandro, Di Cocco Maria Enrica, Bianco Armandodoriano, Golkar Pooran

Targeting serotonin 2A and adrenergic α1receptors for ocular antihypertensive agents. Discovery of 3,4-dihydropyrazino[1,2-b]indazol-1(2H)-one derivatives

pubblicato su: CHEMMEDCHEM - 2018

Furlotti Guido, Alisi Maria Alessandra, Cazzolla Nicola, Ceccacci Francesca, Garrone Beatrice, Gasperi Tecla, La Bella Angela, Leonelli Francesca, Loreto Maria Antonietta, Magarò Gabriele, Mangano Giorgina, Bettolo Rinaldo Marini, Masini Emanuela, Miceli Martina, Migneco Luisa Maria, Vitiello Marco

Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2017

Zwergel Clemens, Czepukojc Brigitte, Evain Bana Emilie, Xu Zhanjie, Stazi Giulia, Mori Mattia, Patsilinakos Alexandros, Mai Antonello, Botta Bruno, Ragno Rino, Bagrel Denise, Kirsch Gilbert, Meiser Peter, Jacob Claus, Montenarh Mathias, Valente Sergio

Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

pubblicato su: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - 2017

Evain Bana Emilie, Schiavo Lucie, Bour Christophe, Lanfranchi Don Antoine, Berardozzi Simone, Ghirga Francesca, Bagrel Denyse, Botta Bruno, Hanquet Gilles, Mori Mattia

Natural modulators of nonalcoholic fatty liver disease: mode of action analysis and in silico ADME-Tox prediction

pubblicato su: TOXICOLOGY AND APPLIED PHARMACOLOGY - 2017

Al Sharif Merilin, Alov Petko, Vitcheva Vessela, Diukendjieva Antonia, Mori Mattia, Botta Bruno, Tsakovska Ivanka, Pajeva Ilza

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting

pubblicato su: DRUG DESIGN, DEVELOPMENT AND THERAPY - 2017

Marianecci Carlotta, Rinaldi Federica, Hanieh PATRIZIA NADIA, Di Marzio Luisa, Paolino Donatella, Carafa Maria

pH-sensitive niosomes: effects on cytotoxicity and on inflammation and pain in murine models

pubblicato su: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - 2017

Rinaldi Federica, Del Favero Elena, Rondelli Valeria, Pieretti Stefano, Bogni Alessia, Ponti Jessica, Rossi François, Di Marzio Luisa, Paolino Donatella, Marianecci Carlotta, Carafa Maria

Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent

pubblicato su: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - 2017

Campestre Cristina, Locatelli Marcello, Guglielmi Paolo, De Luca Elisa, Bellagamba Giuseppe, Menta Sergio, Zengin Gokhan, Celia Christian, Di Marzio Luisa, Carradori Simone

Addiction research and theory: a commentary on the surgeon general's report on alcohol, drugs, and health

pubblicato su: ADDICTION BIOLOGY - 2018

Badiani Aldo, Berridge Kent C., Heilig Markus, Nutt David J., Robinson Terry E.

Intravenous self-administration of benzydamine, a non-steroidal anti-inflammatory drug with a central cannabinoidergic mechanism of action

pubblicato su: ADDICTION BIOLOGY - 2018

Avvisati Riccardo, Meringolo Maria, Stendardo Emiliana, Malavasi Elisa, Marinelli Silvia, Badiani Aldo

The reduction in glutamate release is predictive of cognitive and emotional alterations that are corrected by the positive modulator of AMPA receptors S 47445 in perinatal stressed rats

pubblicato su: NEUROPHARMACOLOGY - 2018

Morley-Fletcher S., Zuena A. R., Mairesse J., Gatta E., Van Camp G., Bouwalerh H., Riozzi B., Battaglia G., Pittaluga A., Olivero G., Mocaer E., Bretin S., Nicoletti F., Maccari S.

Impaired repair of DNA damage is associated with autistic-like traits in rats prenatally exposed to valproic acid

pubblicato su: EUROPEAN NEUROPSYCHOPHARMACOLOGY - 2018

Servadio Michela, Manduca Antonia, Melancia Francesca, Leboffe Loris, Schiavi Sara, Campolongo Patrizia, Palmery Maura, Ascenzi Paolo, di Masi Alessandra, Trezza Viviana

Incubation of methamphetamine but not heroin craving after voluntary abstinence in male and female rats

pubblicato su: NEUROPSYCHOPHARMACOLOGY - 2017

Venniro Marco, Zhang Michelle, Shaham Yavin, Caprioli Daniele

Incubation of extinction responding and cue-induced reinstatement, but not context- or drug priming-induced reinstatement, after withdrawal from methamphetamine

pubblicato su: ADDICTION BIOLOGY - 2017

Adhikary Sweta, Caprioli Daniele, Venniro Marco, Kallenberger Paige, Shaham Yavin, Bossert Jennifer M.

Stress as risk factor for Alzheimer's disease

pubblicato su: PHARMACOLOGICAL RESEARCH - 2018

Caruso Alessandra, Nicoletti Ferdinando, Mango Dalila, Saidi Amira, Orlando Rosamaria, Scaccianoce Sergio

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at ?4?2 nicotinic acetylcholine receptor

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2017

Bolchi Cristiano, Bavo Francesco, Gotti Cecilia, Fumagalli Laura, Fasoli Francesca, Binda Matteo, Mucchietto Vanessa, Sciaccaluga Miriam, Plutino Simona, Fucile Sergio, Pallavicini Marco

Collaboration between a human group and artificial intelligence can improve prediction of multiple sclerosis course. A proof-of-principle study

pubblicato su: F1000RESEARCH - 2018

Tacchella Andrea, Romano Silvia, Ferraldeschi Michela, Salvetti Marco, Zaccaria Andrea, Crisanti Andrea, Grassi Francesca

Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus

pubblicato su: PHARMACOLOGICAL RESEARCH - 2017

Panaccione Isabella, Iacovelli Luisa, DI NUZZO Luigi, Nardecchia Francesca, Mauro Gianluca, Janiri Delfina, DE BLASI Antonio, Sani Gabriele, Nicoletti Ferdinando, Orlando Rosamaria

In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice

pubblicato su: FRONTIERS IN PHARMACOLOGY - 2018

Lattanzi Roberta, Rief Silvia, Schmidhammer Helmut, Negri Lucia, Spetea Mariana.

Sphingosine 1-phosphate receptors: do they have a therapeutic potential in cardiac fibrosis?

pubblicato su: FRONTIERS IN PHARMACOLOGY - 2017

Vestri Ambra, Pierucci Federica, Frati Alessia, Monaco Lucia, Meacci Elisabetta

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Loubidi Mohammed, Jouha Jabrane, Tber Zahira, Khouili Mostafa, Suzenet Franck, Akssira Mohamed, Erdogan Mümin Alper, Köse Fadime Aydın, Dagcı Taner, Armagan Güliz, Saso Luciano, Guillaumet Gérald

Ultramicronized palmitoylethanolamide improves learning and memory in a triple transgenic mouse model of Alzheimer's disease through a combination of anti-inflammatory and neuroprotective effects

pubblicato su: 38th Spanish Society of Pharmacology meeting/9th Spanish Society of Pharmacogenetics and Pharmacogenomics meeting. - 2018

Scuderi Caterina, Bronzuoli MARIA ROSANNA, Facchinetti Roberta, Pace Lorenzo Federico, Canese Rossella, Carpinelli Giulia, Steardo Luca, Cassano Tommaso

Differences in spatial memory recognition due to cognitive style

pubblicato su: FRONTIERS IN PHARMACOLOGY - 2017

Effect of cognitive style on learning and retrieval of navigational environments

pubblicato su: FRONTIERS IN PHARMACOLOGY - 2017

Boccia Maddalena, Vecchione Francesca, Piccardi Laura, Guariglia Cecilia

Effects of pre-reproductive maternal enrichment on maternal care, offspring's play behavior and oxytocinergic neurons

pubblicato su: NEUROPHARMACOLOGY - 2018

Cutuli Debora, Berretta Erica, Caporali Paola, Sampedro-Piquero Patricia, De Bartolo Paola, Laricchiuta Daniela, Gelfo Francesca, Pesoli Matteo, Foti Francesca, Farioli Vecchioli Stefano, Petrosini Laura

SOS response in bacteria. Inhibitory activity of lichen secondary metabolites against Escherichia coli RecA protein

pubblicato su: PHYTOMEDICINE - 2017

Bellio Pierangelo, DI PIETRO Letizia, Mancini Alisia, Piovano Marisa, Nicoletti Marcello, Brisdelli Fabrizia, Tondi Donatella, Cendron Laura, Franceschini Nicola, Amicosante Gianfranco, Perilli Mariagrazia, Celenza Giuseppe

Current trends and outcomes of breast reconstruction following nipple-sparing mastectomy: results from a national multicentric registry with 1006 cases over a 6-year period

pubblicato su: BREAST CANCER - 2017

Casella Donato, Calabrese Claudio, Orzalesi Lorenzo, Gaggelli Ilaria, Cecconi Lorenzo, Santi Caterina, Murgo Roberto, Rinaldi Stefano, Regolo Lea, Amanti Claudio, Roncella Manuela, Serra Margherita, Meneghini Graziano, Bortolini Massimiliano, Altomare Vittorio, Cabula Carlo, Catalano Francesca, Cirilli Alfredo, Caruso Francesco, Lazzaretti Maria Grazia, Meattini Icro, Livi Lorenzo, Cataliotti Luigi, Bernini Marco

Beneficial Effect of Melatonin on Motor and Memory Disturbances in 6-OHDA-Lesioned Rats

pubblicato su: JOURNAL OF MOLECULAR NEUROSCIENCE - 2021

Tancheva Lyubka, Lazarova Maria, Saso Luciano, Kalfin Reni, Stefanova Miroslava, Uzunova Diamara, Atanasov Atanas G.

Flavonoids Targeting HIF-1: Implications on Cancer Metabolism

pubblicato su: CANCERS - 2021

Samec Marek, Liskova Alena, Koklesova Lenka, Mersakova Sandra, Strnadel Jan, Kajo Karol, Pec Martin, Zhai Kevin, Smejkal Karel, Mirzaei Sepideh, Hushmandi Kiavash, Ashrafizadeh Milad, Saso Luciano, Brockmueller Aranka, Shakibaei Mehdi, Büsselberg Dietrich, Kubatka Peter

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study

pubblicato su: BRITISH JOURNAL OF OPHTHALMOLOGY - 2019

Sacchetti M., Lambiase A., Schmidl D., Schmetterer L., Ferrari M., Mantelli F., Allegretti M., Garhoefer G.

Evaluation of the cellular protection by novel spiropyrazole compounds in dopaminergic cell death

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2021

Zaiter Jamila, Hibot Achraf, Hafid Abderrafia, Khouili Mostafa, Neves Claudia M. B., Simões Mário M. Q., Neves M. Graça P. M. S., Faustino M. Amparo F., Dagci Taner, Saso Luciano, Armagan Güliz

Insight into the biological activity of hennosides—glucosides isolated from Lawsonia inermis (henna). Could they be regarded as active constituents instead

pubblicato su: PLANTS - 2021

Maslovarić Irina, Ilić Vesna, Drvenica Ivana, Stančić Ana, Mojsilović Slavko, Kukolj Tamara, Bugarski Diana, Saso Luciano, Nicoletti Marcello

Imidazopyridine hydrazone derivatives exert antiproliferative effect on lung and pancreatic cancer cells and potentially inhibit receptor tyrosine kinases including c-Met

pubblicato su: SCIENTIFIC REPORTS - 2021

Damghani Tahereh, Moosavi Fatemeh, Khoshneviszadeh Mehdi, Mortazavi Motahareh, Pirhadi Somayeh, Kayani Zahra, Saso Luciano, Edraki Najmeh, Firuzi Omidreza

The interaction of flavonols with membrane components: potential effect on antioxidant activity

pubblicato su: THE JOURNAL OF MEMBRANE BIOLOGY - 2020

Saha Sarmistha, Panieri Emiliano, Suzen Sibel, Saso Luciano

Lanthanide (III) complexes of bis-coumarins as strong inhibitors of bovine xanthine oxidase - molecular docking and SAR studies

pubblicato su: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS - 2020

Benarous Khedidja, Bou-Salah Leila, Linani Abderrahmane, Yousfi Mohamed, Kostova Irena, Saso Luciano