Risultati ricerca pubblicazioni

Design, synthesis, and biological evaluation of new 1-(aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2019

Saccoliti Francesco, Madia Valentina Noemi, Tudino Valeria, De Leo Alessandro, Pescatori Luca, Messore Antonella, De Vita Daniela, Scipione Luigi, Brun Reto, Kaiser Marcel, Mäser Pascal, Calvet Alvarez Claudia Magalhaes, Jennings Gareth K, Podust Larissa M, Pepe Giacomo, Cirilli Roberto, Faggi Cristina, Di Marco Annalise, Battista Maria Rosaria, Summa Vincenzo, Costi Roberta, Di Santo Roberto

Novel symmetrical benzazolyl derivatives endowed with potent anti-heparanase activity

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2018

Messore Antonella, Madia Valentina Noemi, Pescatori Luca, Saccoliti Francesco, Tudino Valeria, De Leo Alessandro, Bortolami Martina, De Vita Daniela, Scipione Luigi, Pepi Federico, Costi Roberta, Rivara Silvia, Scalvini Laura, Mor Marco, Ferrara Fabiana Fosca, Pavoni Emiliano, Roscilli Giuseppe, Cassinelli Giuliana, Milazzo Ferdinando M, Battistuzzi Gianfranco, Di Santo Roberto, Giannini Giuseppe

Structure-based drug design of potent pyrazole derivatives against Rhinovirus replication

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2018

Da Costa L., Scheers E., Coluccia A., Casulli A., Roche M., Di Giorgio C., Neyts J., Terme T., Cirilli R., La Regina G., Silvestri R., Mirabelli C., Vanelle P.

In vitro antiviral activity of new oxazoline derivatives as potent poliovirus inhibitors

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2019

Madia Valentina Noemi, Messore Antonella, Pescatori Luca, Saccoliti Francesco, Tudino Valeria, De Leo Alessandro, Scipione Luigi, Fiore Lucia, Rhoden Eric, Manetti Fabrizio, Oberste M Steven, Di Santo Roberto, Costi Roberta

Novel benzazole derivatives endowed with potent antiheparanase activity

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2018

Madia VALENTINA NOEMI, Messore Antonella, Pescatori Luca, Saccoliti Francesco, Tudino Valeria, DE LEO Alessandro, Bortolami Martina, Scipione Luigi, Costi Roberta, Rivara Silvia, Scalvini Laura, Mor Marco, Fosca Ferrara Fabiana, Pavoni Emiliano, Roscilli Giuseppe, Cassinelli Giuliana, M Milazzo Ferdinando, Battistuzzi Gianfranco, DI SANTO Roberto, Giannin Giuseppe

1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

D'Ascenzio M., Secci D., Carradori S., Zara S., Guglielmi P., Cirilli R., Pierini M., Poli G., Tuccinardi T., Angeli A., Supuran C. T.

Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2019

Nawrozkij Maxim B., Forgione Mariantonietta, Yablokov Alexandre S., Lucidi Alessia, Tomaselli Daniela, Patsilinakos Alexandros, PANELLA CRISTINA, Hailu Gebremedhin S., Kirillov Ivan A., Badia Roger, Riveira-Munoz Eva, Crespan Emmanuele, Armijos Rivera Jorge I., Cirilli Roberto, Ragno Rino, Esté José A., Maga Giovanni, Mai Antonello, Rotili Dante

Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2)

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2019

Monaldi Daria, ROTILI Dante, Julien Lancelot ‡, Martin Marek §, Nathalie Wössner ∥, Lucidi Alessia, TOMASELLI DANIELA, Elizabeth Ramos-Morales ‡, Christophe Romier ∥, Pierce ∥ Raymond J., MAI Antonello, and Manfred Jung ‡

Phenyl(thio)phosphon(amid)ate benzenesulfonamides as potent and selective inhibitors of human carbonic anhydrases II and VII counteract allodynia in a mouse model of oxaliplatin-induced neuropathy

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Nocentini A., Alterio V., Bua S., Micheli L., Esposito D., Buonanno M., Bartolucci G., Osman S. M., ALOthman Z. A., Cirilli R., Pierini M., Monti S. M., Di Cesare Mannelli L., Gratteri P., Ghelardini C., De Simone G., Supuran C. T.

Design, palladium-catalyzed synthesis, and biological investigation of 2-substituted 3-aroylquinolin-4(1H)-ones as inhibitors of the Hedgehog signaling pathway.

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2017

Alfonsi Romina, Botta Bruno, Cacchi Sandro, DI MARCOTULLIO Lucia, Fabrizi Giancarlo, Faedda Roberta, Goggiamani Antonella, Iazzetti Antonia, Mori Mattia

Chiral indolylarylsulfone non-nucleoside reverse transcriptase inhibitors as new potent and broad spectrum anti-HIV-1 agents

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2017

Famiglini Valeria, LA REGINA Giuseppe, Coluccia Antonio, Masci Domiziana, Brancale Andrea, Badia Roger, Riveira muã±oz Eva, Estã© Josã© A., Crespan Emmanuele, Brambilla Alessandro, Maga Giovanni, Catalano Myriam, Limatola Cristina, Formica Francesca Romana, Cirilli Roberto, Novellino Ettore, Silvestri Romano

Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Bavo Francesco, Pallavicini Marco, Gotti Cecilia, Appiani Rebecca, Moretti Milena, Colombo Sara Francesca, Pucci Susanna, Viani Paola, Budriesi Roberta, Renzi Massimiliano, Fucile Sergio, Bolchi Cristiano

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Viayna Elisabet, Coquelle Nicolas, Cieslikiewicz-Bouet Monika, Cisternas Pedro, Oliva Carolina A., Sánchez-López Elena, Ettcheto Miren, Bartolini Manuela, De Simone Angela, Ricchini Mattia, Rendina Marisa, Pons Mégane, Firuzi Omidreza, Pérez Belén, Saso Luciano, Andrisano Vincenza, Nachon Florian, Brazzolotto Xavier, García Maria Luisa, Camins Antoni, Silman Israel, Jean Ludovic, Inestrosa Nibaldo C., Colletier Jacques-Philippe, Renard Pierre-Yves, Muñoz-Torrero Diego

Insights into pparγphosphorylation and its inhibition mechanism

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Montanari R., Capelli D., Yamamoto K., Awaishima H., Nishikata K., Barendregt A., Heck A. J. R., Loiodice F., Altieri F., Paiardini A., Grottesi A., Pirone L., Pedone E., Peiretti F., Brunel J. M., Itoh T., Pochetti G.