| Titolo |
Pubblicato in |
Anno |
| P53‐r273h sustains ros, pro‐inflammatory cytokine release and mtor activation while reducing autophagy, mitophagy and ucp2 expression, effects prevented by wtp53 |
BIOMOLECULES |
2021 |
| The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6B |
VIRUS RESEARCH |
2021 |
| PGE2 released by pancreatic cancer cells undergoing ER stress transfers the stress to DCs impairing their immune function |
MOLECULAR CANCER THERAPEUTICS |
2021 |
| Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment |
BIOMEDICINES |
2021 |
| Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53 |
EXPERIMENTAL CELL RESEARCH |
2021 |
| New insights into curcumin-and resveratrol-mediated anti-cancer effects |
PHARMACEUTICALS |
2021 |
| Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21 |
IUBMB LIFE |
2021 |
| HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease |
BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE |
2020 |
| PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR |
BIOMOLECULES |
2020 |
| KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression |
BRITISH JOURNAL OF CANCER |
2020 |
| KSHV dysregulates bulk macroautophagy, mitophagy and UPR to promote endothelial to mesenchymal transition and CCL2 release, key events in viral-driven sarcomagenesis |
INTERNATIONAL JOURNAL OF CANCER |
2020 |
| STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway |
FRONTIERS IN ONCOLOGY |
2020 |
| Viral Infection and Autophagy Dysregulation: The Case of HHV-6, EBV and KSHV |
CELLS |
2020 |
| Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stress |
JOURNAL OF GENERAL VIROLOGY |
2019 |
| Stat3 phosphorylation affects p53/p21 axis and KSHV lytic cycle activation |
VIROLOGY |
2019 |
| Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease? |
NEURAL REGENERATION RESEARCH |
2019 |
| Mutant p53, stabilized by its interplay with HSP90, activates a positive feed-back loop between NRF2 and p62 that induces chemio-resistance to Apigenin in pancreatic cancer cells |
CANCERS |
2019 |
| Kaposi Sarcoma Herpes Virus (KSHV) infection inhibits macrophage formation and survival by counteracting Macrophage Colony-Stimulating Factor (M-CSF)-induced increase of Reactive Oxygen Species (ROS), c-Jun N-terminal kinase (JNK) phosphorylation and autophagy |
THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY |
2019 |
| HHV-6B reduces autophagy and induces ER stress in primary monocytes impairing their survival and differentiation into dendritic cells |
VIRUS RESEARCH |
2019 |
| Quercetin interrupts the positive feedback loop between STAT3 and IL-6, promotes autophagy, and reduces ROS, preventing EBV-driven B cell immortalization |
BIOMOLECULES |
2019 |
