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francesca.ghirga@uniroma1.it
Francesca Ghirga
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
francesca.ghirga@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2020
Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections
MOLECULES
2020
Ent-beyerane diterpenes as a key platform for the development of arnt-mediated colistin resistance inhibitors
JOURNAL OF ORGANIC CHEMISTRY
2020
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma
EXPERT OPINION ON THERAPEUTIC TARGETS
2020
Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia
ACS MEDICINAL CHEMISTRY LETTERS
2019
Stereo- and regioselective gold(i)-catalyzed hydroamination of 2-(arylethynyl)pyridines with anilines
ORGANIC & BIOMOLECULAR CHEMISTRY
2019
Palladium-catalyzed C12-selective direct arylation of [1,2-c] quinazolin-6(5H)-ones
SYNTHESIS
2019
Nigritanine as a new potential antimicrobial alkaloid for the treatment of staphylococcus aureus-induced infections
TOXINS
2019
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth
CANCERS
2019
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
CELL COMMUNICATION AND SIGNALING
2019
Synthesis of pyrano[2,3-: F] chromen-2-ones vs. pyrano[3,2-g] chromen-2-ones through site controlled gold-catalyzed annulations
ORGANIC & BIOMOLECULAR CHEMISTRY
2019
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2018
Palladium-Catalyzed Cascade Approach to 12-(Aryl)indolo[1,2- c ]quinÂazolin-6(5 H )-ones
SYNTHESIS
2018
Synthesis of bromoundecyl resorc[4]arenes and applications of the cone stereoisomer as selector for liquid chromatography
JOURNAL OF ORGANIC CHEMISTRY
2018
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2018
Copper-catalyzed C-N bond formation via C-H functionalization: facile synthesis of multisubstituted imidazo[1,2- a ]pyridines from N -(2-pyridinyl)enaminones
SYNTHESIS
2018
Synthesis of indolo[1,2-c]quinazolines from 2-alkynylaniline derivatives through Pd-catalyzed indole formation/cyclization with N,N-dimethylformamide dimethyl acetal
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
2018
Olefin metathesis reaction as a locking tool for macrocycle and mechanomolecule construction
ORGANIC CHEMISTRY FRONTIERS
2018
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog
CURRENT PHARMACEUTICAL DESIGN
2018
Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro
NANOMEDICINE
2017
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