Francesca Ghirga

Pubblicazioni

Titolo Pubblicato in Anno
Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections MOLECULES 2020
Ent-beyerane diterpenes as a key platform for the development of arnt-mediated colistin resistance inhibitors JOURNAL OF ORGANIC CHEMISTRY 2020
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma EXPERT OPINION ON THERAPEUTIC TARGETS 2020
Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia ACS MEDICINAL CHEMISTRY LETTERS 2019
Stereo- and regioselective gold(i)-catalyzed hydroamination of 2-(arylethynyl)pyridines with anilines ORGANIC & BIOMOLECULAR CHEMISTRY 2019
Palladium-catalyzed C12-selective direct arylation of [1,2-c] quinazolin-6(5H)-ones SYNTHESIS 2019
Nigritanine as a new potential antimicrobial alkaloid for the treatment of staphylococcus aureus-induced infections TOXINS 2019
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth CANCERS 2019
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma CELL COMMUNICATION AND SIGNALING 2019
Synthesis of pyrano[2,3-: F] chromen-2-ones vs. pyrano[3,2-g] chromen-2-ones through site controlled gold-catalyzed annulations ORGANIC & BIOMOLECULAR CHEMISTRY 2019
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2018
Palladium-Catalyzed Cascade Approach to 12-(Aryl)indolo[1,2- c ]quin­azolin-6(5 H )-ones SYNTHESIS 2018
Synthesis of bromoundecyl resorc[4]arenes and applications of the cone stereoisomer as selector for liquid chromatography JOURNAL OF ORGANIC CHEMISTRY 2018
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2018
Copper-catalyzed C-N bond formation via C-H functionalization: facile synthesis of multisubstituted imidazo[1,2- a ]pyridines from N -(2-pyridinyl)enaminones SYNTHESIS 2018
Synthesis of indolo[1,2-c]quinazolines from 2-alkynylaniline derivatives through Pd-catalyzed indole formation/cyclization with N,N-dimethylformamide dimethyl acetal BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY 2018
Olefin metathesis reaction as a locking tool for macrocycle and mechanomolecule construction ORGANIC CHEMISTRY FRONTIERS 2018
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog CURRENT PHARMACEUTICAL DESIGN 2018
Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro NANOMEDICINE 2017
Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2017

Gruppi di ricerca

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