Rita Mancini | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2018
MicroRNAs in melanoma development and resistance to target therapy	ONCOTARGET	2017
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ	ONCOGENE	2017
MicroRNA-driven deregulation of cytokine expression helps development of drug resistance in metastatic melanoma	CYTOKINE & GROWTH FACTOR REVIEWS	2017
BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis	JOURNAL OF TRANSLATIONAL MEDICINE	2017
Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells	CANCER LETTERS	2017
Genetic polymorphism of CHRM2 in COPD. clinical significance and therapeutic implications	JOURNAL OF CELLULAR PHYSIOLOGY	2016
Human lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivity	JOURNAL OF TRANSLATIONAL MEDICINE	2016
Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition	ONCOTARGET	2016
miR-579-3p controls melanoma progression and resistance to target therapy	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA	2016
Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression	ONCOTARGET	2016
Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions	HSOA JOURNAL OF CYTOLOGY & TISSUE BIOLOGY	2016
Review. cell dynamics in malignant pleural effusions	JOURNAL OF CELLULAR PHYSIOLOGY	2015
Superior immunologic and therapeutic efficacy of a xenogeneic genetic cancer vaccine targeting carcinoembryonic human antigen	HUMAN GENE THERAPY	2015
Modified expression of peripheral blood lymphocyte muscarinic cholinergic receptors in asthmatic children	JOURNAL OF NEUROIMMUNOLOGY	2015
Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma	ONCOTARGET	2015
Genetic and Functional Analysis of Polymorphisms in the Human Dopamine Receptor and Transporter Genes in Small Cell Lung Cancer	JOURNAL OF CELLULAR PHYSIOLOGY	2015
Rapid on-site evaluation (ROSE) in pancreatic cancer diagnosis. doing more with less	ONCOCYTOLOGY	2015
The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells	ONCOTARGET	2015
Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway	FREE RADICAL BIOLOGY & MEDICINE	2015

Progetti di Ricerca

Ferroptosis: correlation between STK11-KEAP1 mutations and lipid metabolism in Lung Cancer Stem Cells (LCSCs).
SCD1 as a new target therapeutic and predictive biomarker for lipid metabolism in cancer stem cells
Targeting lipid metabolism to enhance immunogenicity of Cancer Stem Cells
Targeting of SCD1 and mitochondrial functions to revert MAPKi resistance in BRAF-mutated malignant melanoma
Biobanks of primary cultures enriched with Lung Cancer Stem Cells (CSC) and adapted immune cells: targeting lipid metabolism and correlations patients risk factors