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roberta.costi@uniroma1.it
Roberta Costi
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
roberta.costi@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Searching for new agents active against candida albicans biofilm: a series of indole derivatives, design, synthesis and biological evaluation
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2019
Design, synthesis, and biological evaluation of new 1-(aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents
JOURNAL OF MEDICINAL CHEMISTRY
2019
Comparison of different methods for the extraction of cannabinoids from cannabis
NATURAL PRODUCT RESEARCH
2019
Inhibition of Polycomb Repressive Complex2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings
BMC PLANT BIOLOGY
2019
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism
AMINO ACIDS
2019
Towards a new application of amaranth seed oil as an agent against Candida albicans
NATURAL PRODUCT RESEARCH
2019
Tegaserod for the treatment of Irritable Bowel syndrome
ANTI-INFLAMMATORY & ANTI-ALLERGY AGENTS IN MEDICINAL CHEMISTRY
2019
Structure-guided approach identifies a novel class of HIV-1 ribonuclease H inhibitors: binding mode insights through magnesium complexation and site-directed mutagenesis studies
MEDCHEMCOMM
2018
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2018
Novel benzazole derivatives endowed with potent antiheparanase activity
JOURNAL OF MEDICINAL CHEMISTRY
2018
Novel symmetrical benzazolyl derivatives endowed with potent anti-heparanase activity
JOURNAL OF MEDICINAL CHEMISTRY
2018
Functional roles of Acetylated Histone marks at mouse meiotic recombination hotspots
MOLECULAR AND CELLULAR BIOLOGY
2017
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2017
Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase
CHEMMEDCHEM
2017
Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2017
New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2017
Diaryl disulfides as novel stabilizers of tumor suppressor Pdcd4
PLOS ONE
2016
New N,N-dimethylcarbamate inhibitors of acetylcholinesterase: design synthesis and biological evaluation
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2016
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H
ANTIVIRAL RESEARCH
2016
Exploring the anti-biofilm activity of cinnamic acid derivatives in Candida albicans
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
2016
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Progetti di Ricerca
Development of Inhibitors Targeting CoronaViruses-related diseases
Design and Development of novel Heparanase inhibitors able to modulate autophagy
Novel selective inhibitors of ribonuclease H function of the HIV-1 reverse transcriptase enzyme
Innovative small molecules as inhibitors of ribonuclease H function of the HIV-1 reverse transcriptase enzyme
Targeting poverty-related co-infectious diseases through drug lead optimization and combination studies
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