Roberta Gonnella

Pubblicazioni

Titolo Pubblicato in Anno
BFRF1 protein is involved in EBV-mediated autophagy manipulation MICROBES AND INFECTION 2020
Viral Infection and Autophagy Dysregulation: The Case of HHV-6, EBV and KSHV CELLS 2020
EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation AUTOPHAGY 2019
Stat3 phosphorylation affects p53/p21 axis and KSHV lytic cycle activation VIROLOGY 2019
Quercetin interrupts the positive feedback loop between STAT3 and IL-6, promotes autophagy, and reduces ROS, preventing EBV-driven B cell immortalization BIOMOLECULES 2019
EBV up-regulates PD-L1 on the surface of primary monocytes by increasing ROS and activating TLR signaling and STAT3 JOURNAL OF LEUKOCYTE BIOLOGY 2018
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways JOURNAL OF NUTRITIONAL BIOCHEMISTRY 2017
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy SCIENTIFIC REPORTS 2017
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation CELLULAR SIGNALLING 2017
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells FREE RADICAL BIOLOGY & MEDICINE 2017
KSHV reduces autophagy in THP-1 cells and in differentiating monocytes by decreasing CAST/calpastatin and ATG5 expression AUTOPHAGY 2016
Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future BIOMED RESEARCH INTERNATIONAL 2015
PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2015
The activation of KSHV lytic cycle blocks autophagy in PEL cells AUTOPHAGY 2015

ERC

  • LS4_12
  • LS6_5

Interessi di ricerca

Herpesvirus e cancro: ruolo dell'autofagia,  dello stress del reticolo (ER) e UPR (unfolded protein response) nelle neoplasie correlate all'infezione da parte di EBV e KSHV.

Keywords

Herpesviridae Infections
Herpesvirus 4
Herpesvirus 8
macroautophagy
Autophagy/UPR
unfolded protein response (UPR)
primary effusion lymphoma

Progetti di Ricerca

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