Giuseppe Lembo | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Deoxycorticosterone acetate-salt hypertension activates placental growth factor in the spleen to couple sympathetic drive and immune system activation.	CARDIOVASCULAR RESEARCH	2018
From clinical observations to molecular mechanisms and back to patients: The successful circuit of the CANTOS study	CARDIOVASCULAR RESEARCH	2018
The interactions of the immune system and the brain in hypertension	CURRENT HYPERTENSION REPORTS	2018
Brain MRI fiber-tracking reveals white matter alterations in hypertensive patients without damage at conventional neuroimaging	CARDIOVASCULAR RESEARCH	2018
Fatty acids are the best fuel for overloaded hearts	CARDIOVASCULAR RESEARCH	2018
Rivaroxaban for stroke prevention after embolic stroke of undetermined source	NEW ENGLAND JOURNAL OF MEDICINE	2018
Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness	NEW ENGLAND JOURNAL OF MEDICINE	2018
A novel murine model for arrhythmogenic cardiomyopathy points to a pathogenic role of Wnt signaling and miRNA dysregulation	CARDIOVASCULAR RESEARCH	2018
Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)-Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans	ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY	2018
Heart, Spleen, Brain	CIRCULATION	2018
Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial	LANCET NEUROLOGY	2018
PI3kinases in diabetes mellitus and its related complications	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2018
PI3Kγ Inhibition Protects Against Diabetic Cardiomyopathy in Mice	REVISTA ESPAÑOLA DE CARDIOLOGÍA	2017
The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2017
Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling	IMMUNITY	2017
Antiinflammatory therapy with canakinumab for atherosclerotic disease	NEW ENGLAND JOURNAL OF MEDICINE	2017
Pathophysiological Links Among Hypertension and Alzheimer's Disease	HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION	2016
Aliskiren, Enalapril, or Aliskiren and Enalapril in heart failure	NEW ENGLAND JOURNAL OF MEDICINE	2016
Hemorrhagic transformation of acute ischemic stroke is limited in hypertensive patients with cardiac hypertrophy	INTERNATIONAL JOURNAL OF CARDIOLOGY	2016
Flavanol-rich cocoa at breakfast: the right remedy after a sleepless night to prevent negative effects on blood pressure and cognition?	JOURNAL OF HYPERTENSION	2016

ERC

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Biotechnologies and translational approaches applied to cardiovascular disease, neuroscience and immunity.

Keywords

Cardiology and Cardiovascular Medicine

arterial hypertension

Alzheimer's related dementias

brain imaging

adaptive immune responses

Progetti di Ricerca

Investigating the brain-to-spleen axis in hypertensive heart disease: dissection of the neural mechanisms driven by the subfornical organ in the brain circumventricular organs and promoting the splenic immune response recruited to the myocardium.
The neuro immune axis in hypertensive heart disease: novel bioelectronic approaches to investigate in experimental models the role of the autonomic inflammatory pathway in the transition toward heart failure.
Chronic hypertension-induced cerebrovascular damage: identification of novel molecular targets at the immune-vascular interface