Isabella Screpanti | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma	SCIENTIFIC REPORTS	2017
MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs	STEM CELLS INTERNATIONAL	2016
Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression	ONCOGENE	2016
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.	ONCOTARGET	2016
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint	ONCOTARGET	2016
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype	CELL DEATH & DISEASE	2016
A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development	NATURE COMMUNICATIONS	2016
The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease	SCIENTIFIC REPORTS	2016
Notch3 sustains CXCR4 expression in acute T cell lymphoblastic leukemia progression	EUROPEAN JOURNAL OF CANCER	2016
Effect of Argania spinosa oil extract on proliferation and Notch1 and ERK1/2 signaling of T-cell acute lymphoblastic leukemia cell lines	FOOD AND AGRICULTURAL IMMUNOLOGY	2016
Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer.	CLINICAL BIOCHEMISTRY	2015
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors	EMBO JOURNAL	2015
The deregulated expression of miR-125b in acute myeloid leukemia is dependent on the transcription factor C/EBPalpha	LEUKEMIA	2015
Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL	ONCOTARGET	2015
Characterization of medulloblastoma in Fanconi Anemia: a novel mutation in the BRCA2 gene and SHH molecular subgroup	BIOMARKER RESEARCH	2015
The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress	CELL DEATH AND DIFFERENTIATION	2015
Consequences of simulated microgravity in neural stem cells: biological effects and metabolic response.	JOURNAL OF STEM CELL RESEARCH AND THERAPY	2015
Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth	DEVELOPMENTAL CELL	2015
Proteomic analysis of human sonic hedgehog (SHH) medulloblastoma stem-like cells	MOLECULAR BIOSYSTEMS	2015
Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β	ONCOTARGET	2015

Progetti di Ricerca

From thymocyte egression to T-cell Acute Lymphoblastic Leukemia development: identification of new targets for T-ALL therapy