Ilaria Grazia Zizzari

Pubblicazioni

Titolo Pubblicato in Anno
The microbiota impact. bacteria shaping immunity, disease and response to therapy TRANSLATIONAL CANCER RESEARCH 2018
The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one CANCER TREATMENT REVIEWS 2018
Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC? JOURNAL OF TRANSLATIONAL MEDICINE 2018
Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells FRONTIERS IN IMMUNOLOGY 2018
Cross-talk between microbiota and immune fitness to steer and control response to anti PD-1/PDL-1 treatment ONCOTARGET 2017
Tumor-derived microvesicles modulate antigen cross-processing via reactive oxygen species-mediated alkalinization of phagosomal compartment in dendritic cells FRONTIERS IN IMMUNOLOGY 2017
The sexist behaviour of immune checkpoint inhibitors in cancer therapy? ONCOTARGET 2017
Immunomodulatory effects of tyrosine kinase inhibitors (TKIs) in renal cell carcinoma (RCC) patients JOURNAL OF CLINICAL ONCOLOGY 2017
Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: clinical and immunological data of a phase I/II clinical trial INTERNATIONAL JOURNAL OF ONCOLOGY 2016
Potency testing of mesenchymal stromal cell growth expanded in human platelet lysate from different human tissues STEM CELL RESEARCH & THERAPY 2016
Immunological and clinical impact of cancer stem cells in vulvar cancer: role of CD133/CD24/ABCG2-Expressing Cells ANTICANCER RESEARCH 2016
Interleukin-15 enhances cytokine induced killer (CIK) cytotoxic potential against epithelial cancer cell lines via an innate pathway HUMAN IMMUNOLOGY 2016
The macrophage Galactose-type C-type Lectin (MGL) modulates regulatory T cell functions PLOS ONE 2015
MGL receptor and immunity: when the ligand can make the difference JOURNAL OF IMMUNOLOGY RESEARCH 2015

ERC

  • LS6
  • LS6_2
  • LS6_3
  • LS6_11
  • LS7_2

Interessi di ricerca

Studio dei meccanismi di interazione tra tumore e cellule del sistema immunitario.

 

Analisi della fitness immunologica di pazienti con tumori solidi.

 

Vaccinazione anti-tumorale a base peptidica o mediante la somministrazione di cellule dendritiche (DC) autologhe pulsate con proteine ricombinanti o lisato tumorale.

 

Produzione di nuovi immunogeni per la terapia anti-tumore

 

Isolamento ex vivo di immunogeni per la vaccinazione anti-tumore.

 

Monitoraggio Immunologico nei trials clinici di Immunoterapia Sperimentale in Oncologia

Keywords

anticancer immunotherapy
anti-tumor immune response
biomarkers tumor
dendritic cells

Progetti di Ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma