Isabella Screpanti | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Notch3-regulated microRNAs impair CXCR4- CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL	ONCOGENE	2024
Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL	ONCOGENE	2024
The NF-κB1/p50 subunit influences the Notch/IL-6-driven expansion of Myeloid-Derived Suppressor Cells in murine T-Cell Acute Lymphoblastic Leukemia	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey-Hailey disease	EXPERIMENTAL DERMATOLOGY	2023
MicroRNAs as Modulators of the Immune Response in T-Cell Acute Lymphoblastic Leukemia	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Opsonin-deficient nucleoproteic corona Endows unPEGylated liposomes with stealth properties in vivo	ACS NANO	2022
Signaling Crosstalks Drive Generation and Regeneration of the Thymus	FRONTIERS IN IMMUNOLOGY	2022
Notch-Signaling Deregulation Induces Myeloid-Derived Suppressor Cells in T-Cell Acute Lymphoblastic Leukemia	FRONTIERS IN IMMUNOLOGY	2022
5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer: a novel mechanism of intrinsic drug resistance	FRONTIERS IN ONCOLOGY	2022
Editorial: Thymus function and aging: A focus on thymic epithelial cells	FRONTIERS IN IMMUNOLOGY	2022
Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL	CANCERS	2022
miR‑125b/NRF2/HO‑1 axis is involved in protection against oxidative stress of cystic fibrosis: a pilot study	EXPERIMENTAL AND THERAPEUTIC MEDICINE	2021
Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes	CELL DEATH DISCOVERY	2021
Notch signaling in female cancers. A multifaceted node to overcome drug resistance	CANCER DRUG RESISTANCE	2021
Targeting notch to maximize chemotherapeutic benefits: rationale, advanced strategies, and future perspectives	CANCERS	2021
Molecular Mechanisms of Notch Signaling in Lymphoid Cell Lineages Development: NF-κB and Beyond	Notch signaling in Embriology and Cancer	2020
NF-κB1 Regulates Immune Environment and Outcome of Notch-Dependent T-Cell Acute Lymphoblastic Leukemia	FRONTIERS IN IMMUNOLOGY	2020
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response	ONCOGENESIS	2020
NOTCH3 signaling is essential for NF-κB activation in TLR-activated macrophages	SCIENTIFIC REPORTS	2020
A dynamic role of mastermind-like 1: a journey through the main (path)ways between development and cancer	FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY	2020

Progetti di Ricerca

From thymocyte egression to T-cell Acute Lymphoblastic Leukemia development: identification of new targets for T-ALL therapy