| Titolo |
Pubblicato in |
Anno |
| MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation |
ONCOGENE |
2024 |
| SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation |
CELL DEATH DISCOVERY |
2024 |
| Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation |
CANCER LETTERS |
2023 |
| SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma |
CELL DEATH AND DIFFERENTIATION |
2023 |
| ERAP1 as an emerging therapeutic target for medulloblastoma |
TRENDS IN CANCER |
2022 |
| Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors? |
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY |
2022 |
| A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma |
NEUROPATHOLOGY & APPLIED NEUROBIOLOGY |
2022 |
| Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma |
CANCER LETTERS |
2021 |
| Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis |
FRONTIERS IN MOLECULAR NEUROSCIENCE |
2021 |
| The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i |
CANCERS |
2020 |
| The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma |
EXPERT OPINION ON THERAPEUTIC TARGETS |
2020 |
| Dual smo/braf inhibition by flavonolignans from silybum marianum† |
ANTIOXIDANTS |
2020 |
| Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer |
CANCERS |
2020 |
| ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP |
NATURE COMMUNICATIONS |
2019 |
| Targeting hedgehog signalling through the ubiquitylation process: the multiple roles of the HECT-E3 ligase itch |
CELLS |
2019 |
| A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth |
CANCERS |
2019 |
| Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis |
NATURE COMMUNICATIONS |
2018 |
| Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. |
SCIENTIFIC REPORTS |
2017 |
| Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway |
CELL DEATH & DISEASE |
2017 |
| Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma |
SCIENTIFIC REPORTS |
2017 |
