Marianna Nalli

Pubblicazioni

Titolo	Pubblicato in	Anno
4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses	ACS INFECTIOUS DISEASES	2024
Development of N-(4-(1 H-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability	JOURNAL OF MEDICINAL CHEMISTRY	2024
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2023
Hyaluronan-estradiol nanogels as potential drug carriers to target ER+ breast cancer cell line	CARBOHYDRATE POLYMERS	2023
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators	BIOORGANIC CHEMISTRY	2023
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent	ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE	2023
4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells	JOURNAL OF MEDICINAL CHEMISTRY	2023
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2022
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor	JOURNAL OF MEDICINAL CHEMISTRY	2022
Emerging Direct Targeting β-Catenin Agents	MOLECULES	2022
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2021
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme	EUROPEAN JOURNAL OF PHARMACOLOGY	2021
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer	BIOLOGY DIRECT	2021
Discovery of a novel class of norovirus inhibitors with high barrier of resistance	PHARMACEUTICALS	2021
Emerging therapeutic agents for colorectal cancer	MOLECULES	2021
Discovery of new 1,1'-biphenyl-4-sulfonamides as selective subnanomolar human carbonic anhydrase II inhibitors	ACS MEDICINAL CHEMISTRY LETTERS	2020
Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2020
Discovery of Zika virus NS2B/NS3 inhibitors that prevent mice from fife-threatening infection and brain damage	ACS MEDICINAL CHEMISTRY LETTERS	2020
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2020
Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics	JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN	2020

Pubblicazioni

Progetti di Ricerca