Piergiorgio La Rosa | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Vitamin B12 Deficiency and the Nervous System: Beyond Metabolic Decompensation—Comparing Biological Models and Gaining New Insights into Molecular and Cellular Mechanisms	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
Investigating Cerebellar Abnormalities in a mouse model of lysosomal lipid storage disease: Implication for Social Behavior	NEUROLOGY INTERNATIONAL	2024
Cerebellar BDNF signaling downregulation and autistic-like traits: Insights from a cholesterol storage disorder mouse model	Federation of European Neuroscience Societies	2024
A novel approach to treat mitochondrial metabolism dysfunction in Niemann-Pick type C disease	Telethon Institute of Genetic and Medicine	2024
The inactivation of the Niemann Pick C1 cholesterol transporter restricts SARS-CoV-2 entry into host cells by decreasing ACE2 abundance at the plasma membrane.	CELL & BIOSCIENCE	2024
Bromodomain and Extra-Terminal Proteins in Brain Physiology and Pathology: BET-ing on Epigenetic Regulation	BIOMEDICINES	2023
Sex differences in antioxidant defence and the regulation of redox homeostasis in physiology and pathology	MECHANISMS OF AGEING AND DEVELOPMENT	2023
Contribution of A-to-I RNA editing, M6A RNA Methylation, and Alternative Splicing to physiological brain aging and neurodegenerative diseases	MECHANISMS OF AGEING AND DEVELOPMENT	2023
Apparent Opportunities and Hidden Pitfalls: The Conflicting Results of Restoring NRF2-Regulated Redox Metabolism in Friedreich’s Ataxia Pre-Clinical Models and Clinical Trials	BIOMEDICINES	2023
Reduced Cerebellar BDNF Availability Affects Postnatal Differentiation and Maturation of Granule Cells in a Mouse Model of Cholesterol Dyshomeostasis	MOLECULAR NEUROBIOLOGY	2023
Impaired cerebellar development/function in a mouse model of Niemann-Pick C1	20th National Congress of the Italian Society for Neuroscience	2023
Olfaction impairment in lysosomal storage disorders: insights from a mouse model of Niemann Pick type C disease	International Brain Research Organization	2023
Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders	NEUROBIOLOGY OF DISEASE	2022
The cerebellum in Niemann-Pick C1 disease: mouse versus man	CEREBELLUM	2022
EWS splicing regulation contributes to balancing Foxp1 isoforms required for neuronal differentiation	NUCLEIC ACIDS RESEARCH	2022
N-Acetylcysteine Mitigates Social Dysfunction in a Rat Model of Autism Normalizing Glutathione Imbalance and the Altered Expression of Genes Related to Synaptic Function in Specific Brain Areas	FRONTIERS IN PSYCHIATRY	2022
Altered cerebellar BDNF signaling and synaptic anomalies in a mouse model of cholesterol dyshomeostasis	Altered cerebellar BDNF signaling and synaptic anomalies in a mouse model of cholesterol dyshomeostasis	2022
Defective intracellular cholesterol mobilization deranges the proliferation/differentiation balance of neuronal precursors in a mouse model of Niemann Pick C disease	Defective intracellular cholesterol mobilization deranges the proliferation/differentiation balance of neuronal precursors in a mouse model of Niemann Pick C disease	2022
Sex Differences in Autism Spectrum Disorder: Diagnostic, Neurobiological, and Behavioral Features	FRONTIERS IN PSYCHIATRY	2022
The appearance of phagocytic microglia in the postnatal brain of Niemann Pick type C mice is developmentally regulated and underscores shortfalls in fine odor discrimination	JOURNAL OF CELLULAR PHYSIOLOGY	2022

Progetti di Ricerca

Unveiling neurodevelopmental defects of Friedreich Ataxia: new biomarkers and therapeutic opportunities.