Grazia Daniela Raffa

Pubblicazioni

Titolo Pubblicato in Anno
The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening FEBS LETTERS 2022
TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance NATURE COMMUNICATIONS 2022
TGS1 impacts snRNA 3′-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration NUCLEIC ACIDS RESEARCH 2022
Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation CELL REPORTS 2020
Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development PLOS GENETICS 2020
Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements JOURNAL OF MOLECULAR BIOLOGY 2020
Disruption of telomerase RNA maturation kinetics precipitates disease MOLECULAR CELL 2019
The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response NUCLEIC ACIDS RESEARCH 2017
WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models NEUROBIOLOGY OF DISEASE 2017
A role for Separase in telomere protection NATURE COMMUNICATIONS 2016
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence OPEN BIOLOGY 2016
AKTIP/Ft1, a new shelterin-interacting factor required for telomere maintenance PLOS GENETICS 2015
The analysis of pendolino (peo) mutants reveals differences in the fusigenic potential among Drosophila telomeres PLOS GENETICS 2015
Telomere eLS 2015

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