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graziadaniela.raffa@uniroma1.it
Grazia Daniela Raffa
Professore Associato
Struttura:
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "CHARLES DARWIN"
E-mail:
graziadaniela.raffa@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening
FEBS LETTERS
2022
TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance
NATURE COMMUNICATIONS
2022
TGS1 impacts snRNA 3′-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
NUCLEIC ACIDS RESEARCH
2022
Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation
CELL REPORTS
2020
Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development
PLOS GENETICS
2020
Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements
JOURNAL OF MOLECULAR BIOLOGY
2020
Disruption of telomerase RNA maturation kinetics precipitates disease
MOLECULAR CELL
2019
The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response
NUCLEIC ACIDS RESEARCH
2017
WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models
NEUROBIOLOGY OF DISEASE
2017
A role for Separase in telomere protection
NATURE COMMUNICATIONS
2016
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence
OPEN BIOLOGY
2016
AKTIP/Ft1, a new shelterin-interacting factor required for telomere maintenance
PLOS GENETICS
2015
The analysis of pendolino (peo) mutants reveals differences in the fusigenic potential among Drosophila telomeres
PLOS GENETICS
2015
Telomere
eLS
2015
Laboratori di ricerca
CU022_084_85_86_facility allevamento drosophilae
CU022_Lab biologia cellulare
CU022_lab divisione cellulare_CNR
CU022_lab genetica e biologia molecolare
CU022_Laboratorio di Biologia molecolare
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