Our institution has a long-standing tradition in andrological research, with the first academic position being established in Rome in 1981. We have contributed to writing pioneering meta-analyses and national and international guidelines on testosterone replacement therapy (TRT) in male hypogonadism, infertility, and sexual dysfunction. In the past decade, we have focused on developing advanced imaging techniques for testicular disorders. We established the first International School of Ultrasound in Andrology for the European Academy of Andrology. First in the world, we applied contrast-enhanced ultrasonography to testicular tumors.