Pubblicazioni

Structural characterization of murine phosphodiesterase 5 isoforms and involvement of cysteine residues in supramolecular assembly

2023 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Giorgi, Mauro; Miele, Adriana Erica; Cardarelli, Silvia; Giorgi, Alessandra; Massimi, Mara; Biagioni, Stefano; Saliola, Michele

Type 5 phosphodiesterase (PDE5) and the vascular tree: from embryogenesis to aging and disease

2020 - MECHANISMS OF AGEING AND DEVELOPMENT

Cesarini, Valeriana; Guida, Eugenia; Campolo, Federica; Crescioli, Clara; di Baldassarre, Angela; Pisano, Calogera; Balistreri, Carmela Rita; Ruvolo, Giovanni; Jannini, Emmanuele A; Dolci, Susanna

The oligomeric assembly of the phosphodiesterase-5 is a mixture of dimers and tetramers: a putative role in the regulation of function

2018 - BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cardarelli, Silvia; Miele, Adriana Erica; Zamparelli, Carlotta; Biagioni, Stefano; Naro, Fabio; Malatesta, Francesco; Giorgi, Mauro; Saliola, Michele

Phosphodiesterase-5 inhibition preserves renal hemodynamics and function in mice with diabetic kidney disease by modulating miR-22 and BMP7

2017 - SCIENTIFIC REPORTS

Pofi, Riccardo; Fiore, Daniela; De Gaetano, Rita; Panio, G; Gianfrilli, Daniele; Pozza, Carlotta; Barbagallo, Federica; Xiang, Yk; Giannakakis, Konstantinos; Morano, Susanna; Lenzi, Andrea; Naro, Fabio; Isidori, Andrea; Venneri, Mary Anna

Pathways implicated in tadalafil amelioration of duchenne muscular dystrophy

2016 - JOURNAL OF CELLULAR PHYSIOLOGY

DE ARCANGELIS, Valeria; Strimpakos, G.; Gabanella, F.; Corbi, N.; Luvisetto, S.; Magrelli, Armando; Onori, A.; Passananti, C.; Pisani, C.; Rome, S.; Severini, C.; Naro, Fabio; Mattei, E.; Di Certo, M. G.; Monaco, Lucia

PDE5 inhibition ameliorates visceral adiposity targeting the miR-22/SIRT1 pathway: evidence from the CECSID trial

2016 - THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

Fiore, Daniela; Gianfrilli, Daniele; Giannetta, Elisa; Galea, Nicola; Panio, Giuseppe; Di Dato, Carla; Pofi, Riccardo; Pozza, Carlotta; Sbardella, Emilia; Carbone, Iacopo; Naro, Fabio; Lenzi, Andrea; Venneri, Mary Anna; Isidori, Andrea

Inhibition of type 5 phosphodiesterase counteracts Î²2-Adrenergic signalling in beating cardiomyocytes.

2015 - CARDIOVASCULAR RESEARCH

Isidori, Andrea; Cornacchione, M.; Barbagallo, Federica; Di Grazia, A.; Barrios, F.; Fassina, L.; Monaco, Lucia; Giannetta, Elisa; Gianfrilli, Daniele; Garofalo, S.; Zhang, X.; Chen, X.; Xiang, Y. K.; Lenzi, Andrea; Pellegrini, M.; Naro, Fabio

Everything you ever wanted to know about phosphodiesterase 5 inhibitors and the heart (but never dared ask). how do they work

2015 - JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Pofi, Riccardo; Gianfrilli, Daniele; Badagliacca, Roberto; Di Dato, Carla; Venneri, M. A; Giannetta, Elisa; Venneri, Mary Anna