Pubblicazioni

Muscle damage in systemic sclerosis and CXCL10: the potential therapeutic role of PDE5 inhibition

2021 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Corinaldesi, Clarissa; Ross, Rebecca L.; Abignano, Giuseppina; Antinozzi, Cristina; Marampon, Francesco; di Luigi, Luigi; Buch, Maya H.; Riccieri, Valeria; Lenzi, Andrea; Crescioli, Clara; Del Galdo, Francesco

Sildenafil Counteracts the In Vitro Activation of CXCL-9, CXCL-10 and CXCL-11/CXCR3 Axis Induced by Reactive Oxygen Species in Scleroderma Fibroblasts

2021 - BIOLOGY

Antinozzi, Cristina; SgrÃ², Paolo; Marampon, Francesco; Caporossi, Daniela; Del Galdo, Francesco; Dimauro, Ivan; Di Luigi, Luigi

The Phosphodiesterase Type 5 Inhibitor Sildenafil Improves DNA Stability and Redox Homeostasis in Systemic Sclerosis Fibroblasts Exposed to Reactive Oxygen Species

2020 - ANTIOXIDANTS

Di Luigi, Luigi; Duranti, Guglielmo; Antonioni, Ambra; SgrÃ², Paolo; Ceci, Roberta; Crescioli, Clara; Sabatini, Stefania; Lenzi, Andrea; Caporossi, Daniela; Del Galdo, Francesco; Dimauro, Ivan; Antinozzi, Cristina

Chronic administration of sildenafil improves endothelial function in spontaneously hypertensive rats by decreasing COX-2 expression and oxidative stress

2019 - LIFE SCIENCES

Teixeira-da-Silva, JosÃ© Jairo; Nunes-Moreira, Hicla Stefany; Silva, Cristina Oliveira; Lahlou, Saad; Naro, Fabio; Xavier, Fabiano Elias; Duarte, GlÃ³ria Pinto

Chronic phosphodiesterase type 5 inhibition has beneficial effects on subcutaneous adipose tissue plasticity in type 2 diabetic mice

2018 - JOURNAL OF CELLULAR PHYSIOLOGY

Fiore, Daniela; Gianfrilli, Daniele; Cardarelli, Silvia; Naro, Fabio; Lenzi, Andrea; Isidori, Andrea M; Venneri, Mary A

Sildenafil normalizes MALAT1 level in diabetic cardiomyopathy

2018 - ENDOCRINE

Bacci, L.; Barbati, S. A.; Colussi, C.; Aiello, A.; Isidori, A. M.; Grassi, C.; Pontecorvi, A.; Farsetti, A.; Gaetano, C.; Nanni, S.

The cardioprotective effect of sildenafil is mediated by the activation of malate dehydrogenase and an increase in the malate-aspartate shuttle in cardiomyocytes

2017 - BIOCHEMICAL PHARMACOLOGY

Gevi, Federica; Campolo, Federica; Naro, Fabio; Zolla, Lello

Efficacy of 1, 5, and 20mg oral sildenafil in the treatment of adults with pulmonary arterial hypertension. a randomized, double-blind study with open-label extension

2017 - BMC PULMONARY MEDICINE

Vizza, Carmine Dario; Sastry, B. K. S.; Safdar, Zeenat; Harnisch, Lutz; Gao, Xiang; Zhang, Min; Lamba, Manisha; Jing, Zhi Cheng

Sildenafil dosed concomitantly with bosentan for adult pulmonary arterial hypertension in a randomized controlled trial

2017 - BMC CARDIOVASCULAR DISORDERS

Vizza, Carmine Dario; Jansa, Pavel; Teal, Simon; Dombi, Theresa; Zhou, Duo

Use of the KlADH3 promoter for the quantitative production of the murine PDE5A isoforms in the yeast Kluyveromyces lactis

2017 - MICROBIAL CELL FACTORIES

Cardarelli, Silvia; Giorgi, Mauro; Naro, Fabio; Malatesta, Francesco; Biagioni, Stefano; Saliola, Michele

Sildenafil in severe pulmonary hypertension associated with chronic obstructive pulmonary disease. a randomized controlled multicenter clinical trial

2016 - THE JOURNAL OF HEART AND LUNG TRANSPLANTATION

Vitulo, Patrizio; Stanziola, Anna; Confalonieri, Marco; Libertucci, Daniela; Oggionni, Tiberio; Rottoli, Paola; Paciocco, Giuseppe; Tuzzolino, Fabio; Martino, Lavinia; Beretta, Marta; Callari, Adriana; Amaducci, Andrea; Badagliacca, Roberto; Poscia, Roberto; Meloni, Federica; Refini, Rosa Metella; Geri, Pietro; Baldi, Sergio; Ghio, Stefano; D'Alto, Michele; Argiento, Paola; Sofia, Matteo; Guardamagna, Mara; Pizzuto, Beatrice; Vizza, Carmine Dario

Inhibition of type 5 phosphodiesterase counteracts Î²2-Adrenergic signalling in beating cardiomyocytes.

2015 - CARDIOVASCULAR RESEARCH

Isidori, Andrea; Cornacchione, M.; Barbagallo, Federica; Di Grazia, A.; Barrios, F.; Fassina, L.; Monaco, Lucia; Giannetta, Elisa; Gianfrilli, Daniele; Garofalo, S.; Zhang, X.; Chen, X.; Xiang, Y. K.; Lenzi, Andrea; Pellegrini, M.; Naro, Fabio

Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes

2015 - EXPERT OPINION ON THERAPEUTIC TARGETS

Mandosi, Elisabetta; Giannetta, Elisa; Filardi, Tiziana; Lococo, Manuela; Bertolini, Camilla; Fallarino, Mara; Gianfrilli, Daniele; Venneri, MARY ANNA; Lenti, Luisa; Lenzi, Andrea; Morano, Susanna