Ricerc@Sapienza

Rhythm rules everything in our lives, and we believe that circadian biology can offer a key to understanding the unexplained or puzzling evidence in the complexity of endocrine feedback loops. The metabolic consequences of the disruption of clock genes are well-known. We are now adding a further level of complexity, showing how circadian rhythms of the immune system are tightly linked to the endocrine rhythms, especially that of glucocorticoids. The big picture we are in now is that of "neuro-immuno-endocrinology." We love it!