Valerio Consalvi

Publications

Title Published on Year
Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges HUMAN GENETICS 2025
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic variant interpretation methods. GENOME BIOLOGY 2024
The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin THE EUROPEAN PHYSICAL JOURNAL PLUS 2023
Interpretation of missense variants found in association with cancer Encyclopedia of life science 2023
Mutation in the common docking domain affects MAP kinase ERK2 catalysis and stability CANCERS 2023
The complex impact of cancer‑related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants HUMAN GENOMICS 2023
Metal ion binding in wild-type and mutated frataxin: a stability study FRONTIERS IN MOLECULAR BIOSCIENCES 2022
Analysis and interpretation of the impact of missense variants in cancer INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
A glimpse into the structural properties of the intermediate and transition state in the folding of bromodomain 2 d2 by Φ value analysis INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Fondamenti di biochimica umana Fondamenti di biochimica umana 2021
Zn-induced interactions between SARS-CoV-2 orf7a and BST2/Tetherin CHEMISTRYOPEN 2021
Characterization of human frataxin missense variants in cancer tissues HUMAN MUTATION 2019
Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge HUMAN MUTATION 2019
La trascrizione e la traduzione in campo biomedico Sul limite e dei transiti 2018
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme PLOS ONE 2018
PEGylated β-sheet breaker peptides as Inhibitors of β-amyloidf ibrillization CHEMPLUSCHEM 2017
Single-Nucleotide polymorphism of PPARγ, a protein at the crossroads of physiological and pathological processes INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2017
The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process BIOPHYSICAL CHEMISTRY 2017
Unveiling the folding mechanism of the bromodomains BIOCHEMISTRY AND BIOPHYSICS REPORTS 2017
Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy JOURNAL OF TRANSLATIONAL MEDICINE 2016

ERC

  • LS1
  • LS1_2
  • LS1_4

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Keywords

protein stability
missense variants

Progetti di Ricerca

Laboratori di ricerca

Dicroismo circolare

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