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speranzadonatella.rubattu@uniroma1.it
Speranza Donatella Rubattu
Professore Ordinario
Struttura:
DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE
E-mail:
speranzadonatella.rubattu@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Publications
Title
Published on
Year
Very low-calorie ketogenic diet reduces central blood pressure and cardiometabolic risk in post-menopausal women with essential hypertension and obesity: a single-center, prospective, open-label, clinical study
NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
2025
Molecular mechanisms of naringenin modulation of mitochondrial permeability transition acting on F1FO-ATPase and counteracting saline load-induced injury in SHRSP cerebral endothelial cells
EUROPEAN JOURNAL OF CELL BIOLOGY
2024
The potential effect of natural antioxidants on endothelial dysfunction associated with arterial hypertension
FRONTIERS IN CARDIOVASCULAR MEDICINE
2024
Mitochondrial Dysfunction in Heart Failure: From Pathophysiological Mechanisms to Therapeutic Opportunities
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024
Obesity: the perfect storm for heart failure
ESC HEART FAILURE
2024
Role of autophagy in ischemic stroke: insights from animal models and preliminary evidence in the human disease
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2024
UCP2, a Member of the Mitochondrial Uncoupling Proteins: An Overview from Physiological to Pathological Roles
BIOMEDICINES
2024
Early and late gut microbiota signatures of stroke in high salt-fed stroke-prone spontaneously hypertensive rats
SCIENTIFIC REPORTS
2024
Re-analysis of Next-generation Sequencing Data in Patients with Hypertrophic Cardiomyopathy: Contribution of Spliceogenic MYBPC3 Variants in an Italian Cohort
ANNALS OF LABORATORY MEDICINE
2024
Unveiling the spectrum of minor genes in cardiomyopathies: a narrative review
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024
Atrial natriuretic peptide (ANP) modulates stress-induced autophagy in endothelial cells
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
2024
The prognostic role of the echocardiographic tricuspid annular plane systolic excursion/systolic pulmonary arterial pressure (TAPSE/sPAP) ratio and its relationship with NT-proANP plasma level in systemic sclerosis
FRONTIERS IN CARDIOVASCULAR MEDICINE
2023
A Novel Nonsense Pathogenic TTN Variant Identified in a Patient with Severe Dilated Cardiomyopathy
CURRENT ISSUES IN MOLECULAR BIOLOGY
2023
Natriuretic Peptides: It Is Time for Guided Therapeutic Strategies Based on Their Molecular Mechanisms
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
NPPA/atrial natriuretic peptide is an extracellular modulator of autophagy in the heart
AUTOPHAGY
2023
1,5-disubstituted-1,2,3-triazoles counteract mitochondrial dysfunction acting on F1FO-ATPase in models of cardiovascular diseases
PHARMACOLOGICAL RESEARCH
2023
Beneficial Effects of Citrus Bergamia Polyphenolic Fraction on Saline Load-Induced Injury in Primary Cerebral Endothelial Cells from the Stroke-Prone Spontaneously Hypertensive Rat Model
NUTRIENTS
2023
Elabela Peptide: A New Player in Hypertension and Vascular Damage
HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION
2023
Long QTc in hypertrophic cardiomyopathy: A consequence of structural myocardial damage or a distinct genetic disease?
FRONTIERS IN CARDIOVASCULAR MEDICINE
2023
Atrial natriuretic peptide stimulates autophagy/mitophagy and improves mitochondrial function in chronic heart failure
CELLULAR AND MOLECULAR LIFE SCIENCES
2023
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ERC
LS4_10
KET
Life-science technologies & biotechnologies
Interessi di ricerca
Keywords
cardiovascular diseases
molecular mechanisms
animal models
mitochondria
natriuretic peptides
oxidative stress
genetics
autophagy
mitophagy
Progetti di Ricerca
Characterization of novel mechanisms involved in the development of hypertensive cardiac damage: role of mitochondrial dysfunction
Characterization of autophagy as a mechanism mediating renal and vascular protective effects of the mitocondrial Uncoupling Protein 2
Applicazioni della tecnologia "Next Generation Sequencing" nella genomica clinica
Gruppi di ricerca
Disregolazione neurormonale nelle malattie cardiovascolari
Disfunzione mitocondriale e stress ossidativo nelle malattie cardiovascolari
Laboratori di ricerca
Laboratorio di biochimica e genomica
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