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antonello.mai@uniroma1.it
Antonello Mai
Professore Ordinario
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
antonello.mai@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Publications
Title
Published on
Year
Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs)
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2020
Diphenylene Iodonium Is a Noncovalent MAO Inhibitor: A Biochemical and Structural Analysis
CHEMMEDCHEM
2020
HAT inhibitors in cancer therapy
Histone Modifications in Therapy
2020
Lysine Acetyltransferase Inhibitors From Natural Sources
FRONTIERS IN PHARMACOLOGY
2020
Identification of novel quinazoline derivatives as potent antiplasmodial agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2019
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2019
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat
JOURNAL OF PSYCHOPHARMACOLOGY
2019
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones
JOURNAL OF MEDICINAL CHEMISTRY
2019
The emerging role of epigenetics in human autoimmune disorders
CLINICAL EPIGENETICS
2019
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
CLINICAL EPIGENETICS
2019
Sirtuins as drug targets
Epigenetic Drug Discovery
2019
Epigenetic Pharmacology in Regenerative Medicine (Epi-Drugs)
Epigenetics and Regeneration
2019
Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in Rats
FRONTIERS IN MOLECULAR NEUROSCIENCE
2019
Enzymatic and biological characterization of novel sirtuin modulators against cancer
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2)
JOURNAL OF MEDICINAL CHEMISTRY
2019
Epigenetic polypharmacology: a new frontier for epi-drug discovery
MEDICINAL RESEARCH REVIEWS
2019
α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors
ACS MEDICINAL CHEMISTRY LETTERS
2019
DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation
The DNA, RNA, and Histone Methylomes
2019
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype
CLINICAL EPIGENETICS
2019
Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer
CANCERS
2019
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ERC
PE5_18
KET
Life-science technologies & biotechnologies
Interessi di ricerca
Keywords
drug discovery
Epigenetic drugs
antiviral agents
Anticancer drugs
parasite growth inhibition
Progetti di Ricerca
Italian Centre for Native Mass Spectrometry - INCENTIVE MS
Dual- and multi-targeting epigenetic inhibitors for the treatment of aggressive and/or recurrent cancers.
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