Antonello Mai | Ricerc@Sapienza

Publications

Title	Published on	Year
Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells	EUROPEAN JOURNAL OF PHARMACOLOGY	2019
H19-dependent transcriptional regulation of β3 and β4 integrins upon estrogen and hypoxia favors metastatic potential in prostate cancer	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2019
The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells	SCIENTIFIC REPORTS	2019
Histone deacetylases contribute to excitotoxicity-triggered degeneration of retinal ganglion cells in vivo	MOLECULAR NEUROBIOLOGY	2019
Statins and histone deacetylase inhibitors affect lamin A/C - histone deacetylase 2 interaction in human cells	FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY	2019
Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer	CURRENT OPINION IN CHEMICAL BIOLOGY	2019
Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches	JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN	2018
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors	NATURE COMMUNICATIONS	2018
RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer	CLINICAL CANCER RESEARCH	2018
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2	CLINICAL EPIGENETICS	2018
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal	OPEN ACCESS SCIENTIFIC REPORTS	2018
Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice	NEUROSCIENCE	2018
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications	FUTURE MEDICINAL CHEMISTRY	2018
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells	PHILOSOPHICAL TRANSACTIONS - ROYAL SOCIETY. BIOLOGICAL SCIENCES	2018
Trends of LSD1 inhibitors in viral infections	FUTURE MEDICINAL CHEMISTRY	2018
Combined HAT/EZH2 modulation leads to cancer-selective cell death	ONCOTARGET	2018
Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia	ONCOTARGET	2018
Epigenetic metalloenzymes	CURRENT MEDICINAL CHEMISTRY	2018
Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers	PSYCHOPHARMACOLOGY	2018
Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS	AGING CELL	2018

ERC

PE5_18

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Keywords

drug discovery

Epigenetic drugs

antiviral agents

Anticancer drugs

parasite growth inhibition

Progetti di Ricerca

Italian Centre for Native Mass Spectrometry - INCENTIVE MS
Dual- and multi-targeting epigenetic inhibitors for the treatment of aggressive and/or recurrent cancers.