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susanna.scarpa@uniroma1.it
Susanna Scarpa
Professore Ordinario
Struttura:
DIPARTIMENTO DI MEDICINA SPERIMENTALE
E-mail:
susanna.scarpa@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Publications
Title
Published on
Year
Pyrrolyl and indolyl α-γ-diketo acid derivatives acting as selective inhibitors of human carbonic anhydrases IX and XII
PHARMACEUTICALS
2023
Belimumab decreases autophagy and citrullination in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
CELLS
2022
Oxidative stress and visual system a review
EXCLI JOURNAL
2022
The kinesin Eg5 inhibitor K858 exerts antiproliferative and proapoptotic effects and attenuates the invasive potential of head and neck squamous carcinoma cells
INVESTIGATIONAL NEW DRUGS
2022
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
Autophagy Hijacking in PBMC From COVID-19 Patients Results in Lymphopenia
FRONTIERS IN IMMUNOLOGY
2022
Tissue Expression of Androgen Receptor Splice Variant 7 at Radical Prostatectomy Predicts Risk of Progression in Untreated Nonmetastatic Prostate Cancer
ONCOLOGY
2021
Design, synthesis and biological evaluation of new pyrimidine derivatives as anticancer agents
MOLECULES
2021
Anti-tumoral effects of a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative on head and neck squamous carcinoma cell lines
PHARMACEUTICALS
2021
Pro-Inflammatory effects of 1-MHz Pulsed Ultrasound in Human Keratinocytes
5th International Caparica Conference on Ultrasonic-based Applications: from analysis to synthesis 2021
2021
Effect of 1‑MHz ultrasound on the proinflammatory interleukin‑6 secretion in human keratinocytes
SCIENTIFIC REPORTS
2021
Maladaptive autophagy in the pathogenesis of autoimmune epithelitis in Sjögren's syndrome
ARTHRITIS & RHEUMATOLOGY
2021
Discovery of a pyrimidine compound endowed with antitumor activity
INVESTIGATIONAL NEW DRUGS
2020
Androgen receptor variant 7 (AR-V7) in sequencing therapeutic agents for castratrion resistant prostate cancer: A critical review
MEDICINE
2019
Ultrasound delivery of Surface Enhanced InfraRed Absorption active gold-nanoprobes into fibroblast cells: a biological study via Synchrotron-based InfraRed microanalysis at single cell level
SCIENTIFIC REPORTS
2019
Immunotherapy in prostate cancer. Recent advances and future directions
EUROPEAN MEDICAL JOURNAL. UROLOGY
2019
Brain gliomas and growth factors: immunohistochemical, immunofluorescence, flow cytometry and RT-PCR profile in pediatric age
JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS
2019
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype
CLINICAL EPIGENETICS
2019
The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells
INVESTIGATIONAL NEW DRUGS
2018
Growth arrest and apoptosis induced by kinesin Eg5 inhibitor K858 and by its 1,3,4-thiadiazoline analogue in tumor cells
ANTI-CANCER DRUGS
2018
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ERC
LS4_12
Interessi di ricerca
Keywords
antitumor agents
apoptosis
extracellular matrix remodeling
tubulin inhibitors
Progetti di Ricerca
Studio in vitro di nuovi inibitori delle anidrasi carbonica IX e XII come potenziali composti antitumorali.
Studio dell'attività anti-tumorale in vitro di nuovi agenti anti-tubulinici.
Effetti anti-tumorali di inibitori della chinesina Eg5 su glioblastomi umani in vitro.
Terapia epigenetica anti-tumorale del glioblastoma umano in vitro con inibitori dell'istone metil-transferasi EZH2.
Inibizione della chinesina mitotica 5 (Eg5/KIF11/HKSP) come bersaglio per lo sviluppo di farmaci anti tumorali per carcinomi squamosi del distretto cervico-facciale.
Laboratori di ricerca
Patologia Cellulare e Ultrastrutturale
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