Giuseppe Lembo | Ricerc@Sapienza

Publications

Title	Published on	Year
Advanced Magnetic Resonance Imaging to Define the Microvascular Injury Driven by Neuroinflammation in the Brain of a Mouse Model of Hypertension	HYPERTENSION	2024
TGF-β signalling: the Dr. Jekyll and Mr. Hyde of the aortic aneurysms	CARDIOVASCULAR RESEARCH	2024
A Translational Perspective on the Interplay Between Hypertension, Inflammation and Cognitive Impairment	CANADIAN JOURNAL OF CARDIOLOGY	2024
Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure	EUROPEAN HEART JOURNAL	2023
Neuroimmune cardiovascular interfaces control atherosclerosis	NATURE	2022
Frequency and Patterns of Brain Infarction in Patients With Embolic Stroke of Undetermined Source: NAVIGATE ESUS Trial	STROKE	2022
PI3K Isoforms in Vascular Biology, A Focus on the Vascular System-Immune Response Connection	PI3K and AKT Isoforms in Immunity	2022
Ultrasound-guided catheter implantation improves conscious radiotelemetric blood pressure measurement in mice	CARDIOVASCULAR RESEARCH	2021
Chronic 3D vascular-immune interface established by coculturing pressurized resistance arteries and immune cells	HYPERTENSION	2021
Ertugliflozin and slope of chronic egfr prespecified analyses from the randomized vertis cv trial	CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY	2021
A focused review of neural recording and stimulation techniques with immune-modulatory targets	FRONTIERS IN IMMUNOLOGY	2021
The neurology of hypertension: merging academic specialties to connect heart and brain pathophysiology	CARDIOVASCULAR RESEARCH	2021
Neuroimmune interactions in cardiovascular diseases	CARDIOVASCULAR RESEARCH	2020
Brain functional magnetic resonance imaging highlights altered connections and functional networks in patients with hypertension	HYPERTENSION	2020
Identification of a brainstem locus that inhibits tumor necrosis factor	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA	2020
Celiac Vagus Nerve Stimulation Recapitulates Angiotensin II-Induced Splenic Noradrenergic Activation, Driving Egress of CD8 Effector Cells	CELL REPORTS	2020
Cardiovascular Outcomes with Ertugliflozin in Type 2 Diabetes	NEW ENGLAND JOURNAL OF MEDICINE	2020
Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial	LANCET NEUROLOGY	2020
Thioredoxin-1: A cardioprotector against stress	CARDIOVASCULAR RESEARCH	2020
Effects of serelaxin in patients with acute heart failure	NEW ENGLAND JOURNAL OF MEDICINE	2019

ERC

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Keywords

Cardiology and Cardiovascular Medicine

arterial hypertension

Alzheimer's related dementias

brain imaging

adaptive immune responses

Progetti di Ricerca

Investigating the brain-to-spleen axis in hypertensive heart disease: dissection of the neural mechanisms driven by the subfornical organ in the brain circumventricular organs and promoting the splenic immune response recruited to the myocardium.
The neuro immune axis in hypertensive heart disease: novel bioelectronic approaches to investigate in experimental models the role of the autonomic inflammatory pathway in the transition toward heart failure.
Chronic hypertension-induced cerebrovascular damage: identification of novel molecular targets at the immune-vascular interface