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laviniavittoria.lotti@uniroma1.it
Lavinia Vittoria Lotti
Professore Ordinario
Struttura:
DIPARTIMENTO DI MEDICINA SPERIMENTALE
E-mail:
laviniavittoria.lotti@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Publications
Title
Published on
Year
Antitumour effects of SFX-01 molecule in combination with ionizing radiation in preclinical and in vivo models of rhabdomyosarcoma
BMC CANCER
2024
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival
EXPERIMENTAL AND MOLECULAR MEDICINE
2024
Prevention of prostate cancer metastasis by a CRISPR-delivering nanoplatform for interleukin-30 genome editing
MOLECULAR THERAPY
2024
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery
CELLS
2023
ZnO Nanorods Create a Hypoxic State with Induction of HIF-1 and EPAS1, Autophagy, and Mitophagy in Cancer and Non-Cancer Cells
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
Inactivation of interleukin-30 in colon cancer stem cells via CRISPR/Cas9 genome editing inhibits their oncogenicity and improves host survival
JOURNAL FOR IMMUNOTHERAPY OF CANCER
2023
Assessing the Impact of Polyethylene Nano/Microplastic Exposure on Human Vaginal Keratinocytes
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality
JOURNAL OF HEMATOLOGY & ONCOLOGY
2022
Samhd1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity
PLOS PATHOGENS
2020
Diameters and fluorescence calibration for extracellular vesicle analyses by flow cytometry
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Ultrastructure study of skin fibroblasts in patients with ehlers-danlos syndrome (EDS): preliminary results
LA CLINICA TERAPEUTICA
2020
A developmental perspective on paragangliar tumorigenesis
CANCERS
2019
Pmr-1 gene affects susceptibility of Caenorhabditis elegans to Staphylococcus aureus infection through glycosylation and stress response pathways alterations
VIRULENCE
2019
Sourcing the immune system to induce immunogenic cell death in Kras-colorectal cancer cells
BRITISH JOURNAL OF CANCER
2019
Tympanojugular Paragangliomas: Surgical Management and Clinicopathological Features
Paraganglioma: A Multidisciplinary Approach [Internet]. Brisbane (AU): Codon Publications
2019
Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib
ACTA NEUROPATHOLOGICA
2018
Enhanced platelet MRP4 expression and correlation with platelet function in patients under chronic aspirin treatment
THROMBOSIS AND HAEMOSTASIS
2016
Tyrosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells
CANCER LETTERS
2015
Impact of chronic exposure to bevacizumab on EpCAM-based detection of circulating tumor cells
CHINESE JOURNAL OF CANCER RESEARCH
2015
ERC
LS1
LS1_9
LS3_1
LS3_6
LS4_12
KET
Life-science technologies & biotechnologies
Interessi di ricerca
Keywords
malattie rare
morfologia
BASI BIOLOGICHE DEL CANCRO
Progetti di Ricerca
Caratterizzazione di un herpesvirus CMV-simile identificato nei parangliomi e valutazione del potenziale oncogeno in relazione al tipo cellulare di origine del tumore.
Interazioni fra infezione virale e differenziamento cellulare nella patogenesi del paraganglioma/feocromocitoma.
Caratterizzazione immunomorfologica ed ultrastrutturale del paraganglioma della base cranica mediante lo sviluppo di modelli sperimentali in vitro e in vivo.
Laboratori di ricerca
Biopatologia ultrastrutturale
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