antibacterial agents

Laboratorio di biochimica e analisi strutturale

Laboratorio di biochimica e analisi strutturale

The Lab is runed by 3 peers: Carlo Travaglini Allocatelli, Giorgio Giardina and Adele Di Matteo

WHAT: The Lab is focused on the determination of 3D protein structures at the atomic level and on the analysis of protein folding and miss-folding process including beta-amyloid formation. 

SYNLAB

SYNLAB

The early work of Botta group was devoted to the structural elucidation and synthesis of biological active molecules derived from plant in vivo. Since 1984, his group have been working in the field of in vitro plant tissue cultures. The general aim of the investigation was directed toward the understanding of biosynthetic pathways of the isolated metabolites and the isolation of the responsible enzymes. During this research, new plant enzymes (e.g. peroxidases) have been isolated, purified, and characterized by chemical and kinetic studies.

Antimicrobial effects of chemically functionalized and/or photo-heated nanoparticles

Antibiotic resistance refers to when microorganisms survive and grow in the presence of specific antibiotics, a phenomenon mainly related to the indiscriminate widespread use and abuse of antibiotics. In this framework, thanks to the design and fabrication of original functional nanomaterials, nanotechnology offers a powerful weapon against several diseases such as cancer and pathogenic illness. Smart nanomaterials, such as metallic nanoparticles and semiconductor nanocrystals, enable the realization of novel drug-free medical therapies for fighting against antibiotic-resistant bacteria.

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