epigenetic changes

Epigenetic alterations in aging and in endocrine and metabolic diseases

Epigenetic alterations in aging and in endocrine and metabolic diseases

Aging and endocrine-metabolic diseases are complex conditions characterized by profound epigenetic alterations that affect gene expression and cellular function. Epigenetic mechanisms, such as DNA methylation and hydroxymethylation, play a central role in the adaptation of cells to environmental and metabolic stimuli.

Sex hormones and inflammation role in oral cancer progression. A molecular and biological point of view

Oral cancers have been proven to arise from precursors lesions and related to risk behaviour such as alcohol consumption and smoke. However, the present paper focus on the role of chronic inflammation, related with chronical oral infections and/or altered immune responses occurring during dysimmune and autoimmune diseases, in the oral cancerogenesis.

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