CIDP | Ricerc@Sapienza

Atypical CIDP: diagnostic criteria, progression and treatment response. Data from the Italian CIDP database

Objectives: A few variants of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) have been described, but their frequency and evolution to typical CIDP remain unclear. To determine the frequency and characteristics of the CIDP variants, their possible evolution to typical CIDP, and treatment response. Methods: We applied a set of diagnostic criteria to 460 patients included in a database of Italian patients with CIDP. Clinical characteristics and treatment response were reviewed for each patient.

Chronic inflammatory demyelinating polyradiculoneuropathy: can we make a diagnosis in patients not fulfilling electrodiagnostic criteria?

Background and purpose: The aim was to identify the clinical and diagnostic investigations that may help to support a diagnosis of chronic inﬂammatory demyelinating polyradiculoneuropathy (CIDP) in patients not fulﬁlling the European Federation of Neurological Societies and Peripheral Nerve Society(EFNS/PNS) electrodiagnostic criteria.Methods: The data from patients with a clinical diagnosis of CIDP included in a national database were retrospectively reviewed.Results: In all, 535 patients with a diagnosis of CIDP were included.

Frequency of diabetes and other comorbidities in chronic inflammatory demyelinating polyradiculoneuropathy and their impact on clinical presentation and response to therapy

OBJECTIVES: To determine the prevalence of different comorbidities in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and their impact on outcome, treatment choice and response. METHODS: Using a structured questionnaire, we collected information on comorbidities from 393 patients with CIDP fulfilling the European Federation of Neurological Societies and Peripheral Nerve Society criteria included in the Italian CIDP database.

Impact of environmental factors and physical activity on disability and quality of life in CIDP

A few observational studies and randomized trials suggest that exercise and rehabilitation may improve activity limitation and quality of life (QoL) in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), but the impact of other modifiable factors on the severity of the disease is not well understood. Using a structured questionnaire, we collected data on lifestyle and dietary habits of the patients included in the Italian CIDP database to investigate the possible influence of modifiable lifestyle factors on disability and QoL.