Ricerc@Sapienza

In 1923 at the Royal Theatre English Opera House of London started the journey of the mute Frankenstein of Thomas Potter Cook. On that stage the creature born from the encounter between science and romantic genius definitively lost his voice to progressively assume more and more the appearance of a body that speaks for itself, beyond literary fact, and above all beyond verbal language.

DNA is an entity shielded by mechanisms that maintain genomic stability and are essential for living cells; however, DNA is constantly subject to assaults from the environment throughout the cellular life span, making the genome susceptible to mutation and irreparable damage. Cells are prepared to mend such events through cell death as an extrema ratio to solve those threats from a multicellular perspective. However, in cells under various stress conditions, checkpoint mechanisms are activated to allow cells to have enough time to repair the damaged DNA.

Tra le sfide che caratterizzano la decrescita sostenibile dei centri urbani, un importante contributo alla definizione degli scenari futuri è dato dalle incertezze legate ai cambiamenti climatici. Le possibili azioni da intraprendere richiedono un ampio grado di adattabilità per incrementare la resilienza, ristabilendo il rapporto bidirezionale tra l’inevitabile interazione “uomo<->modifiche<->ambiente”.