ADHD

Iperacusia pediatrica

Iperacusia pediatrica

Le attività di questo gruppo di ricerca si concentrano sullo studio dell'iperacusia nel bambino, con particolare attenzione alla diagnosi e all'associazione con altre condizioni patologiche neuropsichiatriche. 

L’iperacusia è un’intolleranza ai suoni quotidiani di intensità normale o moderata che provoca notevoli disturbi e danni alle attività sociali, professionali, ricreative e altre attività quotidiane. I pazienti con iperacusia percepiscono i suoni con intensità moderata ed elevata come intollerabilmente forti o addirittura dolorosi.

Comorbidity of Attention Deficit Hyperactivity Disorder and Generalized Anxiety Disorder in children and adolescents

The aim of the study is to explore the impact of Generalized Anxiety Disorder (GAD) comorbidity in children
with Attention Deficit Hyperactivity Disorder (ADHD).
Six hundred children with ADHD (mean age=9.12 years), recruited from 2013 to 2017, participated in the
study. A total of 96 (16%) children with ADHD displayed a comorbidity with GAD. ADHD+GAD were compared
to 504 ADHD children without GAD in terms of cognitive and psychiatric profile, ADHD subtype and
family psychiatric history.

Relations Between Sleep and Temperament in Preschool Children With ADHD

Objective: The objective of this study was to assess the links between temperament and sleep in a group of preschoolers with ADHD. Method: Twenty-five ADHD (M = 5.37 years, SD = 1.09) and 22 typically developing (TD; M = 5.10, SD = 1.18) preschoolers participated in the study. Sleep was assessed with the Sleep Disturbance Scale and wrist actigraphy. The Preschool Temperament and Character Inventory (PsTCI) was used to evaluate the child temperament.

Relations Between Sleep and Temperament in Preschool Children With ADHD

Objective: The objective of this study was to assess the links between temperament and sleep in a group of preschoolers with ADHD. Method: Twenty-five ADHD (M = 5.37 years, SD = 1.09) and 22 typically developing (TD; M = 5.10, SD = 1.18) preschoolers participated in the study. Sleep was assessed with the Sleep Disturbance Scale and wrist actigraphy. The Preschool Temperament and Character Inventory (PsTCI) was used to evaluate the child temperament.

Sleep paralysis in two children with attention deficit hyperactivity disorder

We describe for the first time the presence of SP in two children with ADHD that was associated with the presence of a sinister shadowy "bedroom intruder" that sometimes attacked the sleeper. The "creature" was lurking in the distant dark, slowly approaching and appearing as a dark shadow, similar to the human size and shape. 4

Sleep EEG oscillations in neurodevelopmental disorders without intellectual disabilities

Neurodevelopmental disorders (NDDs) are often characterised by sleep problems, and recent evidence indicates alterations of the sleep electroencephalographic (EEG) oscillations in these patients. Sleep microstructure plays a crucial role in cognitive functioning and brain maturation. In this view, modifications in sleep EEG oscillations in NDDs could further impair the cognitive maturation process in these patients.

Evaluation of relational reasoning by a transitive inference task in attention-deficit/hyperactivity disorder

Objective: Here we explored whether children with ADHD have a deficit in relational reasoning, a skill subtending the acquisition of many cognitive abilities and social rules. Method: We analyzed the performance of a group of children with ADHD during a transitive inference task, a task requiring first to learn the reciprocal relationship between adjacent items of a rank ordered series (e.g., A>B; B>C; C>D; D>E; E>F), and second, to deduct the relationship between novel pairs of items never matched during the learning (e.g., B>D; C>E).

Dopamine–mediated immunomodulation affects choroid plexus function

Immune system alterations have been implicated in various dopamine-related disorders, such as schizophrenia, bipolar disorder, and attention-deficit/hyperactivity disorder (ADHD). How immunity might be influenced by dopaminergic dysfunction and impact on clinically-relevant behaviors is still uncertain. We performed a peripheral and cerebral immunophenotyping in mice bearing dopaminergic alteration produced by genetic liability (hypofunction of the dopamine transporter DAT) and psychostimulant (amphetamine) administration.

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