Ricerc@Sapienza

Objective: Chronic kidney disease (CKD) is a condition with high cardiovascular mortality associated with emerging risk factors, including sarcopenia. Several mechanisms can affect muscle mass, such as vitamin D deficiency, low protein intake, physical inactivity, metabolic acidosis, and inflammation leading to a worsening of cardiovascular outcomes and cognitive function.

Background: Few data are available regarding longitudinal changes of cardiac structure and function in end-stage chronic kidney disease (CKD). Aim of the present study is to describe serial echocardiographic findings in a cohort of dialyzed CKD patients. Methods: In this retrospective longitudinal study, we included n = 120 dialyzed CKD patients who underwent at least 2 echocardiograms either 1, 2 or 3 years apart. After baseline echocardiogram, n = 112 had a further examination at year 1, n = 76 at year 2 and n = 45 at year 3.

Abstract: In patients suffering from moderate-to-severe chronic kidney disease (CKD) or end-stage renal disease (ESRD), subjected to hemodialysis (HD), pain is very common, but often underestimated. Opioids are still the mainstay of severe chronic pain management; however, their prescription in CKD and HD patients is still significantly low and pain is often under-treated. Altered pharmacokinetics and the lack of clinical trials on the use of opioids in patients with renal impairment increase physicians’ concerns in this specific population.

Introduction: Chronic kidney disease (CKD) is a highly prevalent condition and it is a
major risk factor for end-stage renal disease (ESRD), cardiovascular disease, and premature death.
Some congenital and acquired anomalies of the kidneys and lower urinary tract (CAKUT and
CALUT) are well-known causes of CKD and ESRD, but often remain undiagnosed and their
prevalence is underestimated. This study aims to provide an overview that considered mainly
some of the major congenital and acquired urological diseases that could lead to renal clinical

Background. Chronic kidney disease (CKD) is a highly prevalent condition. Urologic disorders are known causes of CKD, but
often remain undiagnosed and underestimated also for their insidious onset and slow progression. We aimed to evaluate
the prevalence of urological unrecognized diseases in CKD patients by uroflowmetry. Methods. We enrolled consecutive stable CKD outpatients. The patients carried out two questionnaires, the International
Prostate Symptom Score and Incontinence Questionnaire-Short Form, and they also underwent uroflowmetry, evaluating

Introduction: Chronic Kidney Disease (CKD) is a highly prevalent condition and it is a major risk factor for End-Stage Renal Disease (ESRD), cardiovascular disease, and premature death. Some congenital and acquired anomalies of the kidneys and lower urinary tract (CAKUT and CALUT) are well-known causes of CKD and ESRD, but often remain undiagnosed and their prevalence is underestimated.

Introduction Children with unilateral renal tumor (URT) and preoperative renal
dysfunction (PRD) may benefit from nephron-sparing surgery (NSS). To test this
hypothesis, we studied the outcome of baseline renal function after nephrectomy or
NSS among children with URT.
Materials and Methods Retrospective records review of children with URT who
underwent nephrectomy (25 children) or NSS (11 children) at our institution. We
analyzed the estimated glomerular filtration rate (eGFR) changes over time among