Ricerc@Sapienza

Novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) became pandemic by the end of March 2020. In contrast to the 2002–2003 SARS-CoV outbreak, which had a higher pathogenicity and lead to higher mortality rates, SARSCoV-2 infection appears to be much more contagious. Moreover, many SARS-CoV-2 infected patients are reported to develop low-titer neutralizing antibody and usually suffer prolonged illness, suggesting a more effective SARS-CoV-2 immune surveillance evasion than SARS-CoV.

The Covid-19 epidemic is having a strong impact on the population with pre-existing chronic diseases. The collision between the Covid-19 pandemic and the current diabesity epidemic has highlighted that obese and diabetic patients have a worse prognosis due to the impairment of the immune response to infections and due to the mechanical limits that make the management of the hospitalized patients with severe obesity more difficult.

The novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has generated the ongoing coronavirus disease-2019 (COVID-19) pandemic, still with an uncertain outcome. Besides pneumonia and acute lung injury (ALI) or acute respiratory distress syndrome (ARDS), other features became evident in the context of COVID-19. These includes endothelial and coagulation dysfunction with disseminated intravascular coagulation (DIC), and multiple organ dysfunction syndrome (MODS), along with the occurrence of neurological alterations.

The diagnosis of coronavirus disease 2019 (COVID-19) relies on nasopharyngeal swab, which shows a 20–30% risk of false negativity [1]. Bronchoalveolar lavage (BAL) is reported to be useful in patients with pulmonary interstitial infiltrates on high-resolution computed tomography (HRCT). We investigated the usefulness of BAL in symptomatic patients with positive HRCT and a repeatedly negative swab test (‘grey zone’).

Editoriale del n. 2, dedicato alle trasformazione nel ruolo e funzioni della biblioteca dopo la pandemia da coronavirus

L'attuale sovraffollamento costituisce un fattore esponenziale del rischio epidemia: rende estremamente difficile la prevenzione; quasi impossibile il contenimento e la cura del contagio. Se si vuole evitare che la situazione sfoci in una conclusione drammatica è anzitutto necessario, sebbene naturalmente non sufficiente, che la popolazione detenuta torni entro i limiti della recettività penitenziaria.

Appunto per l’audizione presso l’Ufficio di Presidenza della Commissione Affari Costituzionali sul tema: «Modalità più efficaci per l'esercizio delle prerogative costituzionali del Parlamento nell'ambito di un'emergenza dichiarata» - giovedì 12 novembre 2020

Lo scritto, nel sottolineare la centralità della dimensione territoriale delle istituzioni, si occupa delle problematiche principali sottese alla questione di Roma Capitale, tanto più rilevanti in un momento in cui sono sul tappeto fondi cospicui grazie al Recovery Fund per venire a capo della crisi provocata dal Coronavirus.

The impact of Coronavirus (COVID-19) on head and neck cancer patients' care.

Aim: The aim of the present study was to take a survey on Italian practitioners concerning the perceived risks of aerosol contamination in COVID-19 times and their attitude toward modifications of treatment protocols to reduce this risk. Materials and methods: Power analysis calculated a minimum sample size of 150 participants at 99% confidence level with a 5% margin of error. To homogenize responses elicited by different preventive measures by various national governments, only Italian dentists were included in the survey: overall 500 responses were collected.